|1.||Palazzo, Enza: 5 articles (06/2014 - 09/2008)|
|2.||Maione, Sabatino: 5 articles (06/2014 - 09/2008)|
|3.||de Novellis, Vito: 3 articles (06/2014 - 03/2011)|
|4.||Duvoisin, Robert M: 3 articles (04/2013 - 07/2005)|
|5.||Pilc, A: 2 articles (09/2015 - 02/2007)|
|6.||Marabese, Ida: 2 articles (06/2014 - 03/2011)|
|7.||Rossi, Francesca: 2 articles (06/2014 - 03/2011)|
|8.||Luongo, Livio: 2 articles (06/2014 - 03/2011)|
|9.||Giordano, Catia: 2 articles (06/2014 - 03/2011)|
|10.||Boccella, Serena: 2 articles (06/2014 - 03/2011)|
06/01/2014 - "mGluR8 proved also to be overexpressed in pain controlling areas during pathological pain guaranteeing the availability of a switch for turning off abnormal pain. "
06/01/2014 - "The development of (S)-3,4-dicarboxyphenylglycine, a selective mGluR8 agonist, has revealed the mGluR8 role in inhibiting pain and its related affective consequences in chronic pain conditions. "
12/01/2011 - "Presynaptic mGluR8 inhibits pain-related enhanced excitatory transmission in the CeLC."
03/23/2011 - "These results show that stimulation of mGluR8, which was overexpressed within the CeA in inflammatory pain conditions, inhibits nociceptive behavior. "
06/01/2014 - "This review will focus on the novel insights into the mGluR8 role on pain control, with particular emphasis on the supraspinal descending pathway, an antinociceptive endogenous source, whose activation or disinhibition (via mGluR8) induces analgesia."
09/01/2008 - "During epilepsy a significant down-regulation (P < 0.01) of mGluR8 gene expression was observed which was up-regulated (P < 0.05) near control level after B. "
09/01/2008 - "We investigated the role of metabotropic glutamate-8 receptor (mGluR8) gene expression in cerebellum during epilepsy and neuroprotective role of Bacopa monnieri extract in epilepsy. "
03/15/2003 - "In this study we analyzed the function of presynaptic mGluR8 on terminals of the lateral perforant pathway in the pilocarpine model of limbic epilepsy. "
03/01/2000 - "No association found between polymorphisms in genes encoding mGluR7 and mGluR8 and idiopathic generalised epilepsy in a case control study."
03/06/1999 - "Since there is no evidence of altered L-AP4 responses, a loss of group III mGluR function, particularly that of subtype mGluR8, seems not necessary for the kindling epilepsy."
|3.||Schizophrenia (Dementia Praecox)
06/04/2007 - "These data provide a potential role for mGluR8 in anxiety and suggest that mGluR8 may not be a therapeutic target for schizophrenia."
06/04/2007 - "We have established the localization of the group III mGluR subtype, mGluR8, in the human body and investigated the biological effects of the selective mGluR8 agonist (S)-3,4-dicarboxyphenylglycine ((S)-3,4-DCPG) in schizophrenia-related animal models. "
01/15/2001 - "We conducted association studies to investigate the novel Tyr433Phe (mGluR7) variant and the 2846-C/T (mGluR8) polymorphism in schizophrenia. "
01/15/2001 - "Both variants, present at high frequencies, failed to demonstrate any significant association with schizophrenia (mGluR7 [Tyr433Phe] allele: P=0.33; genotype: P=0.63; mGluR8 [2846-C/T] allele: P=0.72; genotype: P=0.63)."
|4.||Neuralgia (Stump Neuralgia)
06/01/2014 - "Dorsal striatum metabotropic glutamate receptor 8 affects nocifensive responses and rostral ventromedial medulla cell activity in neuropathic pain conditions."
06/01/2014 - "The present study investigated the role of metabotropic glutamate receptor subtype 8 (mGluR8) in the dorsal striatum (DS) in modulating thermonociception and rostral ventromedial medulla (RVM) ON and OFF cell activities in conditions of neuropathic pain induced by spared nerve injury (SNI) of the sciatic nerve in rats. "
10/25/2015 - "[Metabotropic glutamate receptor 8 activation promotes the apoptosis of lung carcinoma A549 cells in vitro]."
10/25/2015 - "This study aims to detect the expression of metabotropic glutamate receptors (mGluRs) in lung carcinoma A549 cells, and to investigate the effects of mGluR8 and mGluR4 activation on the growth of A549 cells in vitro. "
|1.||metabotropic glutamate receptor 7
|2.||Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)
|3.||metabotropic glutamate receptor 4
|4.||Glutamic Acid (Glutamate)
|6.||Terminator Codon (Termination Codon)
|7.||Serotonin (5 Hydroxytryptamine)
|8.||Immunoglobulin E (IgE)
|9.||gamma-Aminobutyric Acid (GABA)
|10.||DNA (Deoxyribonucleic Acid)