HOME
PRODUCTS
COMPANY
CONTACT
FAQ
Research
Dictionary
Pharma
Sign Up
FREE
or
Login
Username:
Password:
Remember login
Login
Send password reminder...
4- amino- (2- methyl- 4- aminophenyl)benzamide
structure in first source
Also Known As:
4A-2M4A-PB
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amides: 2428
Benzamides: 115
4-amino-(2-methyl-4-aminophenyl)benzamide: 1
Hydrocarbons: 1713
Cyclic Hydrocarbons: 97
Aromatic Hydrocarbons: 291
Benzene Derivatives: 17
Benzoates: 426
Benzamides: 115
4-amino-(2-methyl-4-aminophenyl)benzamide: 1
Carboxylic Acids: 973
Carbocyclic Acids
Benzoates: 426
Benzamides: 115
4-amino-(2-methyl-4-aminophenyl)benzamide: 1
Related Diseases
1.
Seizures (Absence Seizure)
01/01/1998 - "
After intraperitoneal administration to mice, 4-amino-(2-methyl-4-aminophenyl)benzamide was found active in the maximal electroshock seizure test and against the tonic seizures elicited either by bicuculline or 3-mercaptopropionic acid.
"
01/01/1998 - "
4-amino-(2-methyl-4-aminophenyl)benzamide (4A-2M4A-PB) gave anti maximal electroshock seizures ED50 of 63 micromol/kg (15.4 mg/kg) and a TD50 of 676 micromol/kg (163 mg/kg), yielding a PI of 10.7; the potency is similar to that of the 4-amino-(2-methyl-3-aminophenyl)phthalimide (4A-2M3A-PP), superior to that of 4-amino-(2,6-dimethylphenyl)phthalimide (4A-2,6-DMPP), close to that of phenytoin and carbamazepine and inferior to that of ameltolide.
"
Related Drugs and Biologics
1.
3-Mercaptopropionic Acid (3 Mercaptopropionic Acid)
2.
Phenytoin (Dilantin)
3.
Carbamazepine (Tegretol)
4.
Bicuculline
5.
ameltolide