NSR 0430

02/01/1999 - "In conclusion, our in vitro and in vivo results demonstrate that administration of NSR 0430 substantially improves liver-to-tumor CNR and lesion detection on T2-weighted magnetic resonance images even in the presence of severe cirrhosis."
03/01/1998 - "NSR 0430 caused a T2 relaxation time decrease in the control animals by 49%; in the CCl4 group with light and moderate liver fibrosis, by 25%; in the CCl4 group with severe liver fibrosis or cirrhosis, by 16%; and in the TAA group with cirrhosis, by 30%. "
02/01/1999 - "The purpose of this study was to determine the diagnostic value of the superparamagnetic iron oxide NSR 0430 for the detection of focal liver lesions in the presence of advanced cirrhosis. "
03/01/1998 - "Enhancement of the superparamagnetic contrast agent NSR 0430 is decreased in the presence of liver fibrosis and cirrhosis in an animal model. "
03/01/1998 - "The enhancement characteristics and the diagnostic value of a cell-specific superparamagnetic contrast agent (NSR 0430) in different degrees of liver fibrosis and cirrhosis were experimentally studied in an animal model. "

02/01/1999 - "In conclusion, our in vitro and in vivo results demonstrate that administration of NSR 0430 substantially improves liver-to-tumor CNR and lesion detection on T2-weighted magnetic resonance images even in the presence of severe cirrhosis."
02/01/1999 - "Enhanced tumor detection in the presence of liver cirrhosis: experimental study on the diagnostic value of a superparamagnetic iron oxide MR imaging contrast agent (NSR 0430)."

02/01/1999 - "Enhanced tumor detection in the presence of liver cirrhosis: experimental study on the diagnostic value of a superparamagnetic iron oxide MR imaging contrast agent (NSR 0430)."

09/01/1996 - "The aim of the study was to compare the first-passage profiles of dysprosium diethylenetriamine penta-acetic acid bis(methylamide) (DTPA BMA) and the superparamagnetic iron oxide particles NSR 0430 in regions with severe and moderate cerebral ischemia. "

09/01/1996 - "In this rat stroke model, dysprosium DTPA BMA and the superparamagnetic iron oxide particles NSR 0430 were found to be equally efficacious for the diagnosis of the perfusion deficit, but if safe for human investigations, iron oxide particles would have an advantage as equal susceptibility effect may be achieved with smaller injection volumes."