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4- (benzyloxy)- 2,6- diamino- 5- nitropyrimidine

a pyrimidine derivative that inhibit human O(6)-alkylguanine-DNA alkyltransferase (AGAT); structure in first source
Also Known As:
NO-BP
Networked: 18 relevant articles (1 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Elley, C Raina: 2 articles (01/2010 - 01/2010)
2. Warren, Jim: 2 articles (01/2010 - 01/2010)
3. Kennelly, John: 2 articles (01/2010 - 01/2010)
4. Paton, Chris: 2 articles (01/2010 - 01/2010)
5. Mabotuwana, Thusitha: 2 articles (01/2010 - 01/2010)
6. Wells, Stewart: 2 articles (01/2010 - 01/2010)
7. Ozturk, Gunseli: 1 article (01/2015)
8. Yaman, Banu: 1 article (01/2015)
9. Iskandarli, Mehdi: 1 article (01/2015)
10. Gerceker Turk, Bengu: 1 article (01/2015)

Related Diseases

1. Hypertension (High Blood Pressure)
01/01/1999 - "In conclusion, correction of RAS leads to cure of or improved control of hypertension in the majority of the patients with FMD, but in the ASC group in about half of cases no BP cure or improvement was seen. "
06/01/2013 - "Individuals aged >70 years with a history of systolic hypertension on 1 or no BP lowering drugs were recruited from primary care (n=37; age, 75±4 years; systolic BP, >150 mm Hg) and randomized to receive intensive (target BP, <130/80 mm Hg) or usual (target BP, <140/85 mm Hg) BP lowering for 12 weeks, with reviews every 2 weeks. "
01/01/2010 - "Data from two New Zealand general practices was analysed on five BP control indicators for patients with diagnosed hypertension: 1) last BP high (>150/90 mmHg); 2) last BP high or no BP measurement; 3) two or more consistently high BP measurements for ≥ 90 days; 4) a high BP then lapse of >120 days in BP measurement; and 5) antihypertensive medication possession ratio (MPR) of <80%. "
01/01/2010 - "Data were analysed for three indicators with respect to a nine-month evaluation period for patients with hypertension and a 15-month period for patients with diabetes: (1) two or more consistently high BP measurements spaced over > or = 90 days, (2) a high BP measurement followed by a lapse of >120 days in BP measurement and (3) no BP measurement for >180 days. "
11/01/2009 - "Hypertension was recorded in 119.065 individuals (prevalence 19.3%), 19.134 (16%) had no ambulatory visit and 33.183 (27.8%) had no BP value recorded. "
2. Osteoporosis
3. Fatigue
4. Prostatic Neoplasms (Prostate Cancer)
5. Tachycardia (Tachyarrhythmias)

Related Drugs and Biologics

1. Methotrexate (Mexate)
2. SB 203580

Related Therapies and Procedures

1. Catheters
2. Sympathectomy (Sympathectomies)