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ubiquitin C-terminal 7-amido-4-methylcoumarin

a fluorogenic substrate for deubiquitinating enzymes

Also Known As:

Ub-AMC

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        ubiquitin C-terminal 7-amido-4-methylcoumarin: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        ubiquitin C-terminal 7-amido-4-methylcoumarin: 1
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Ubiquitins: 125
    - ubiquitin C-terminal 7-amido-4-methylcoumarin: 1

Experts

1.	Feng, Xing: 1 article (01/2019)
2.	He, Ruixing: 1 article (01/2019)
3.	Hong, Xuehui: 1 article (01/2019)
4.	Huang, He: 1 article (01/2019)
5.	Jia, Yanyan: 1 article (01/2019)
6.	Jin, Junfei: 1 article (01/2019)
7.	Li, Qinghua: 1 article (01/2019)
8.	Ma, Fei: 1 article (01/2019)
9.	Piao, Daxun: 1 article (01/2019)
10.	Qiu, Xingfeng: 1 article (01/2019)

Related Diseases

1.

Hepatocellular Carcinoma (Hepatoma)

01/01/2019 - "Abbreviations: ATG: autophagy related; BafA1: bafilomycin A1; BECN1: beclin 1; CHX: cycloheximide; CSNK1A1/CK1α: casein kinase 1 alpha 1; CQ: chloroquine; DUB: deubiquitinase; EBSS: Earle's balanced salt solution; EGF: epidermal growth factor; GFP: green fluorescent protein; GST: glutathione S-transferase; HBSS: Hanks balanced salts solution; HCC: hepatocellular carcinoma; MAP1LC3B/LC3: microtubule associated protein 1 light chain 3 beta; MEFs: mouse embryo fibroblasts; mRFP: monomeric red fluorescent protein; PIK3C3/VPS34: phosphatidylinositol 3-kinase catalytic subunit type 3; PTMs: post-translational modifications; RUBCN: rubicon autophagy regulator; siRNA: small interfering RNA; SMURF1: SMAD specific E3 ubiquitin protein ligase 1; SQSTM1: sequestosome 1; Ub-AMC: ubiquitin-7-amido-4-methylcoumarin: a fluorogenic substrate; UVRAG: UV radiation resistance associated; ZRANB1/TRABID: zinc finger RANBP2-type containing 1."

Related Drugs and Biologics

1.	Class III Phosphatidylinositol 3-Kinases
2.	Green Fluorescent Proteins
3.	Casein Kinase I (Casein Kinase 1)
4.	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)
5.	Small Interfering RNA (siRNA)
6.	Ubiquitin
7.	Solutions
8.	Salts
9.	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)
10.	Glutathione Transferase (Glutathione S-Transferase)