|1.||Lai, Henry C: 2 articles (11/2010 - 11/2005)|
|2.||Singh, Narendra P: 2 articles (11/2005 - 01/2005)|
|3.||Wang, Qiuyan: 1 article (01/2015)|
|4.||Zhao, Xindong: 1 article (01/2015)|
|5.||Huo, Lanfen: 1 article (01/2015)|
|6.||Zhao, Hongguo: 1 article (01/2015)|
|7.||Wu, Shaoling: 1 article (01/2015)|
|8.||Zhao, Chunting: 1 article (01/2015)|
|9.||Jiang, Jin-ping: 1 article (12/2013)|
|10.||Yu, He-ping: 1 article (12/2013)|
12/01/2013 - "Furthermore, we observed that holotransferrin significantly enhanced the anti-cancer activity of artemisinin. "
01/28/2005 - "We found that holotransferrin-tagged artemisinin, when compared with artemisinin, was very potent and selective in killing cancer cells. "
01/28/2005 - "Effects of artemisinin-tagged holotransferrin on cancer cells."
05/04/1995 - "Selective cancer cell cytotoxicity from exposure to dihydroartemisinin and holotransferrin."
12/01/2013 - "This study is aimed to investigate the selective inhibitory effects of artemisinin on SMMC-7721 cells in vitro and determine the effect of holotransferrin, which increases the concentration of ferrous iron in cancer cells, combined with artemisinin on the anticancer activity. "
10/01/1997 - "These studies have demonstrated pathways whereby one urinary protein, holotransferrin, may alter proximal tubular cell function and cause tubular cytotoxicity, and at least two urinary proteins, albumin and transferrin, may mediate the development of interstitial inflammation in proteinuric renal disease."
|4.||Hemochromatosis (Bronze Diabetes)
04/01/2008 - "Three studies demonstrate the importance of the IRE-IRP system for enterocytes in balancing extracellular iron demand against cellular iron requirements, show that the hemochromatosis protein HFE exerts its iron-regulatory activity principally in hepatocytes by modulating the production of hepcidin, and provide strong support for a proposed mechanism of transcriptional regulation of hepcidin through a signaling cascade initiated by holotransferrin displacing HFE from transferrin receptor 1."
11/01/2010 - "After pretreatment with 12 μM holotransferrin, Molt-4 human leukemia cells were cultured in 10 μM artemisinin and exposed for 90 min to one of three different conditions: control, room air control, and HBO(2). "
11/01/2005 - "Molt-4 cells (a human lymphoblastoid leukemia cell line) and freshly isolated human lymphocytes, cultured in complete RPMI-1640 medium, were first incubated with 12 microM of human holotransferrin at 37 degrees C in a humid atmosphere of 5% CO2 for one hour to enhance the iron concentration in the cells. "
05/04/1995 - "Rapid cell death, as evidenced by a decrease in cell counts, was observed when molt-4-lymphoblastoid cells, a human leukemia cell line, were exposed to holotransferrin (12 microM) and dihydroartemisinin (1-200 microM). "
|4.||Transferrin (beta 2 Transferrin)
|5.||Transferrin Receptors (Transferrin Receptor)
|7.||Proteins (Proteins, Gene)
|9.||Antisense RNA (Anti-Sense RNA)
|10.||Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)