galactosyl- (1,4)- fucopyranosyl- (1,3)- N- acetylglucosamine

Also Known As:

Galbeta(1,4)(Fucalpha(1,3))GlcNAc; Lewis X trisaccharide; Lewis(x) trisaccharide GFG; beta-D-Galp-1-4(alpha-L-Fucp-1-3)-beta-D-GlcpNAc

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Carbohydrates: 22023
- Polysaccharides: 15383
  - Oligosaccharides: 3566
    - Trisaccharides: 123
      - galactosyl-(1,4)-fucopyranosyl-(1,3)-N-acetylglucosamine: 4
Biological Factors: 2472
- Biomarkers: 240291
  - Tumor Biomarkers: 15272
    - Carbohydrate Tumor-Associated Antigens: 355
      - Lewis X Antigen: 164
        galactosyl-(1,4)-fucopyranosyl-(1,3)-N-acetylglucosamine: 4
  - Differentiation Antigens: 2082
    - Myelomonocytic Differentiation Antigens: 1
      - Lewis X Antigen: 164
        galactosyl-(1,4)-fucopyranosyl-(1,3)-N-acetylglucosamine: 4
- Antigens: 143924

Experts

1.	Choi, Beak-San: 1 article (05/2014)
2.	Harn, Donald: 1 article (05/2014)
3.	Norberg, Thomas: 1 article (05/2014)
4.	Srivastava, Leena: 1 article (05/2014)
5.	Tundup, Smanla: 1 article (05/2014)
6.	Fu, Da: 1 article (09/2010)
7.	Hu, Ping: 1 article (09/2010)
8.	Jia, Cheng-You: 1 article (09/2010)
9.	Wu, Wei: 1 article (09/2010)
10.	Wu, Xing Zhong: 1 article (09/2010)

Related Diseases

1.	Neoplasms (Cancer) 06/08/2007 - "Both human and mouse SRCL are highly specific for the Lewis(x) trisaccharide, which is commonly found on the surfaces of leukocytes and some tumor cells. " 04/01/2023 - "This spatially-differential distribution of core and shell in one cell ensures the effective inhibition of intracellular sialyltransferase to downregulate immunosuppressing sialic acid, and direct presentation of NK-activating Lewis X trisaccharide (LeX) on tumor surface simultaneously. "
2.	Psoriasis (Pustulosis Palmaris et Plantaris) 05/01/2014 - "LNFPIII conjugates and schistosome egg antigens, which contain the Lewis(x) trisaccharide, drive alternative activation of APCs and induce anti-inflammatory responses in vivo, preventing inflammation-based diseases, including psoriasis, transplant organ rejection, and metabolic disease. "
3.	Metabolic Diseases (Metabolic Disease) 05/01/2014 - "LNFPIII conjugates and schistosome egg antigens, which contain the Lewis(x) trisaccharide, drive alternative activation of APCs and induce anti-inflammatory responses in vivo, preventing inflammation-based diseases, including psoriasis, transplant organ rejection, and metabolic disease. "
4.	Inflammation (Inflammations) 05/01/2014 - "LNFPIII conjugates and schistosome egg antigens, which contain the Lewis(x) trisaccharide, drive alternative activation of APCs and induce anti-inflammatory responses in vivo, preventing inflammation-based diseases, including psoriasis, transplant organ rejection, and metabolic disease. "
5.	Hepatocellular Carcinoma (Hepatoma) 09/14/2010 - "To investigate the role of Gal3ST-2 and its product 3'-sulfo-Le(x), we depleted Gal3ST-2 via siRNA and added exogenous Lewis-x trisaccharide 3'-sulfate sodium salt in human SMMC7721 hepatoma cells. "

Related Drugs and Biologics

1.	Small Interfering RNA (siRNA)
2.	N-Acetylneuraminic Acid (Sialic Acid)
3.	Sodium
4.	Sialyltransferases
5.	Salts
6.	Antigens
7.	lacto-N-fucopentaose III