|1.||Henshall, David C: 2 articles (06/2011 - 04/2004)|
|2.||Simon, Roger P: 2 articles (06/2011 - 04/2004)|
|3.||Meller, Robert: 2 articles (06/2011 - 04/2004)|
|4.||Nie, Wei: 1 article (09/2015)|
|5.||Wei, Hua: 1 article (09/2015)|
|6.||Li, Bing: 1 article (09/2015)|
|7.||Chen, Wan-Sheng: 1 article (09/2015)|
|8.||Chen, Wan-sheng: 1 article (09/2015)|
|9.||Tao, Xia: 1 article (09/2015)|
|10.||Cai, Jia-Yi: 1 article (01/2015)|
|1.||B-Cell Lymphoma (Lymphoma, B Cell)
01/01/2012 - "The B-cell lymphoma 2 interacting mediator of cell death (Bim) protein was dispensable for proapoptotic response to BITC in MCF-7 and MDA-MB-231 cells as judged by RNA interference studies. "
10/01/2013 - "Bcl-2-interacting mediator of cell death (Bim) is a pro-apoptotic B-cell lymphoma 2 family member implicated in numerous apoptotic stimuli. "
03/01/2013 - "Finally, we demonstrated that WEV+NP robustly decreased the expression of anti-apoptotic effectors, such as B cell Lymphoma-2 (Bcl-2), B cell Lymphoma-extra large (Bcl-(XL)) and myeloid cell leukemia sequence-1 (Mcl-1), and increased the expression of pro-apoptotic effectors, such as Bcl-2 homologous antagonist/killer (Bak), Bcl-2-associated X protein (Bax) and Bcl-2-interacting mediator of cell death (Bim). "
01/01/2015 - "In addition, treatment of K562/ADR cells with quercetin alone or in combination with ADR resulted in loss of mitochondrial membrane potential, activation of caspase-8, -9 and -3, reduced expression of the anti-apoptotic proteins B-cell lymphoma (Bcl)-2 and Bcl-extra large and enhanced expression of the pro-apoptotic proteins Bcl-2-interacting mediator of cell death, Bcl-2-associated death promoter and Bcl-2-associated X protein in the cells. "
|2.||Melanoma (Melanoma, Malignant)
03/01/2014 - "For patients who agreed to provide peripheral blood or tumor tissue, we analyzed the genotype of Bcl-2-interacting mediator of cell death (BIM) deletion polymorphism and EGFR mutation status. "
06/01/2012 - "We harnessed the natural killing activity of BCL-2-interacting mediator of cell death (BIM), which contains one of the most potent BH3 death domains of the BCL-2 protein family, to restore BH3-dependent cell death in resistant hematologic cancers. "
03/18/2011 - "Furthermore, BH3-M6 disrupts Bcl-X(L)/Bim, Bcl-2/Bim, and Mcl-1/Bim protein-protein interactions and frees up Bim to induce apoptosis in human cancer cells that depend for tumor survival on the neutralization of Bim with Bcl-X(L), Bcl-2, or Mcl-1. "
12/28/2014 - "A local injection of the AuNP-Apt loaded with the apoptosis-inducing BIM protein efficiently inhibited the growth of xenograft tumors in mice. "
12/01/2014 - "HTLV-1 infection of human T cells also reduced their levels of Bim protein, and restoring Bim expression in HTLV-1-infected cells reduced their proliferation by inducing apoptosis. "
01/17/2008 - "Infection of EBV-negative BL cells with this panel of EBVs and challenge with various cytotoxic drugs showed that EBNA3A and EBNA3C cooperate as the main determinants of both drug resistance and the downregulation of the proapoptotic Bcl-2-family member Bcl-2-interacting mediator of cell death (Bim). "
08/01/2011 - "In addition, the expression of the proapoptotic Bim protein in thymocytes was not changed, revealing that the parasite infection-induced thymus atrophy has no effect on these marker genes necessary to promote clonal deletion of T cells. "
10/04/2004 - "During infection with both species, Chlamydia trachomatis and Chlamydia pneumoniae, Bim protein gradually disappeared without noticeable changes in Bim mRNA. "
01/01/2011 - "In mixed splenocyte populations the vigorous immune cell survival promoting effects of KLK6 were shown to include both T and B lymphocytes, to occur with as little as 5 minutes of treatment, and to involve up regulation of the pro-survival protein B-cell lymphoma-extra large (Bcl-XL), and inhibition of the pro-apoptotic protein Bcl-2-interacting mediator of cell death (Bim). "
12/01/2012 - "Resistance was associated with a partial reactivation of extracellular signal-regulated kinase 1/2 (ERK1/2) signaling, recovery of G1/S cell-cycle events, and suppression of the pro-apoptotic B-cell leukemia/lymphoma 2 (Bcl-2) homology domain 3 (BH3)-only proteins, Bcl-2-interacting mediator of cell death-extra large (Bim-EL) and Bcl-2 modifying factor (Bmf). "
|1.||Proteins (Proteins, Gene)
|3.||bcl-2-Associated X Protein (bcl 2 Associated X Protein)
|4.||Messenger RNA (mRNA)
|5.||Bcl-2-like protein 11
|7.||Fas Ligand Protein (Fas Ligand)
|8.||Caspase 8 (Caspase-8)
|9.||Apoptosis Regulatory Proteins
|10.||Mitogen-Activated Protein Kinase 3
|1.||Heterologous Transplantation (Xenotransplantation)