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FR 901379

a water- soluble Echinocandin compound; structure in first source

Also Known As:

FR-901379; FR901379

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - FR 901379: 3
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - FR 901379: 3

Experts

1.	Hashimoto, Seiji: 1 article (12/2009)
2.	Isogai, Yasuhiro: 1 article (12/2009)
3.	Orino, Yohsuke: 1 article (12/2009)
4.	Shimosaka, Makoto: 1 article (12/2009)
5.	Taguchi, Goro: 1 article (12/2009)
6.	Ueda, Satoshi: 1 article (12/2009)
7.	Yamada, Masato: 1 article (12/2009)
8.	Yawata, Kazunobu: 1 article (12/2009)
9.	Barrett, David: 1 article (07/2002)

Related Diseases

1.	Mycoses (Diseases, Fungus) 12/01/2009 - "The filamentous fungus Coleophoma empetri F-11899 produces an echinocandin-like compound FR901379, the original source for micafungin which is prescribed to treat deep-seated mycoses. " 07/18/2002 - "In our search for natural products with a broad spectrum of antifungal activity as lead compounds for novel treatments for mycoses, we have isolated echinocandin-type lipopeptide FR901379 and lipopeptidolactone FR901469, as novel water-soluble antifungal agents that inhibit the synthesis of 1,3-beta-glucan, a key component of the fungal cell wall. "
2.	Invasive Fungal Infections 10/26/2023 - "To date, three kinds of echinocandins for caspofungin, anidulafungin, and micafungin, which derived from pneumocandin B0 , echinocandin B, and FR901379, are commercially available in clinic and have shown potential in managing invasive fungal infections in a cost-effective manner. "

Related Drugs and Biologics

1.	Echinocandins
2.	Micafungin (FK463)
3.	Lipopeptides
4.	Antifungal Agents
5.	Anidulafungin
6.	Caspofungin (Cancidas)
7.	lipopeptidolactone
8.	FR 901469
9.	pneumocandin B(0)
10.	beta-1,3-glucan