|1.||Kim, So Hee: 2 articles (06/2003 - 12/2002)|
|2.||Lee, Myung Gull: 2 articles (06/2003 - 12/2002)|
|3.||Kim, Eun Jung: 2 articles (06/2003 - 12/2002)|
|4.||Chung, Hye Chin: 2 articles (06/2003 - 12/2002)|
|5.||Kim, Sang Geon: 2 articles (06/2003 - 12/2002)|
|6.||Zeldin, Darryl C: 1 article (10/2012)|
|7.||Henry, Michael A: 1 article (10/2012)|
|8.||Hargreaves, Kenneth M: 1 article (10/2012)|
|9.||Roman, Linda: 1 article (10/2012)|
|10.||Patil, Mayur: 1 article (10/2012)|
|1.||Acute Kidney Injury (Acute Renal Failure)
01/01/2004 - "Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of 2-(allylthio) pyrazine, a chemoprotective agent, in rats: the role of CYP3A23 induction."
12/01/2002 - "In rats with acute renal failure induced by uranyl nitrate, the hepatic microsomal cytochrome P450 (CYP) 2E1 and CYP3A23 increased 2-4- and 4-times, respectively, CYP2C11 decreased to 80% of control, but the levels of CYP1A2 and CYP2B1/2 were not changed. "
06/01/2003 - "The purpose of this study is to report the changes of CYP2E1, CYP1A2, CYP2B1/2, CYP2C11, CYP3A23, and CYP3A2 expression and pharmacokinetics and tissue distribution of chlorzoxazone (CZX) and 6-hydroxychlorzoxazone (OH-CZX) in rats with acute renal failure induced by uranyl nitrate (U-ARF), and the role of CYP3A23 and CYP3A2 in the formation of OH-CZX in rats with U-ARF. "
12/01/2008 - "Effects of intrauterine undernutrition on the expression of CYP3A23/3A1, PXR, CAR and HNF4alpha in neonate rats."
12/01/2008 - "In conclusion, these findings suggest that undernutrition may influence the mRNA expression of CAR and protein expression of both CYP3A23/3A1 and CAR in neonatal rats. "
12/01/2008 - "The present study investigated the effects of undernutrition in utero on hepatic mRNA and protein expression of the enzyme CYP3A23/3A1 and nuclear receptors including pregnane X receptor (PXR; NR1I2), constitutive androstane receptor (CAR; NR1I3) and nuclear factor-4alpha (HNF4alpha; HNF4A) in neonatal rats. "
|3.||Hepatocellular Carcinoma (Hepatoma)
07/01/2012 - "The suitability of rat hepatoma cell line H4IIE for evaluating the potentials of compounds to induce CYP3A23 expression."
07/01/2003 - "2. Host cell effects were investigated by trans-species transient transfection of reporter genes containing either the rat CYP3A23 or human CYP3A4 proximal promoters into human HepG2 and rat FaO and H4IIEC3 hepatoma cells. "
|4.||Body Weight (Weight, Body)
02/15/2005 - "Quantitative real time RT-PCR assays of rat hepatic RNA samples from animals treated at the 150 mg/kg body weight/day dose revealed significant mRNA overexpression of the following genes compared to control: CYP1A2 (1.62-fold), CYP2B1 (10.8-fold), CYP3A1/CYP3A23 (2.78-fold), and CYP3A2 (1.84-fold). "
01/01/2005 - "quinquefolius extracts did not affect body weight gain, absolute or relative liver weight, hepatic CYP2B1, CYP3A23, or CYP1A2 mRNA expression, or microsomal CYP2B-mediated 7-benzyloxyresorufin O-dealkylation (BROD) or CYP1A-mediated 7-ethoxyresorufin O-dealkylation (EROD) activity. "
|1.||Cytochrome P-450 CYP1A2 (CYP1A2)
|2.||Cytochrome P-450 CYP2B1 (PROD)
|4.||Messenger RNA (mRNA)
|5.||Cytochrome P-450 CYP2E1 (CYP2E1)
|6.||Cytoplasmic and Nuclear Receptors (Nuclear Receptors)
|8.||constitutive androstane receptor
|9.||pregnane X receptor