plumieride

RN refers to (1S-(1alpha,4aalpha,7alpha(R*),7aalpha))-isomer; from Allamanda cathartica & Himatanthus fallax; structure in first source

Networked: 4 relevant articles (1 outcomes, 1 trials/studies)

1.	Andrade, Sérgio Faloni de: 1 article (03/2018)
2.	Boeing, Thaise: 1 article (03/2018)
3.	Bonomini, Tiago José: 1 article (03/2018)
4.	Lucinda, Ruth Meri: 1 article (03/2018)
5.	Malheiros, Angela: 1 article (03/2018)
6.	Mariano, Luísa Nathália Bolda: 1 article (03/2018)
7.	Somensi, Lincon Bordignon: 1 article (03/2018)
8.	da Silva, Luísa Mota: 1 article (03/2018)
9.	de Souza, Priscila: 1 article (03/2018)
10.	Aggarwal, Ved Prakash: 1 article (11/2014)

1.	Weight Loss (Weight Reduction) 03/01/2018 - "Plumieride, at dose of 100?mg/kg, significantly attenuated the mice weight loss, showed lower score in the disease activity index, diminished the colon shortening, improved the histological damage and avoided mucosa intestinal mucus depletion when compared with vehicle-treated only group. "
2.	Ulcerative Colitis 03/01/2018 - "Taking together, the results of the present study disclose that plumieride exhibited a significant efficacy in attenuating the parameters of experimental ulcerative colitis, which may be mediated by an antioxidant and anti-inflammatory effect."
3.	Body Weight (Weight, Body) 11/27/2014 - "Simultaneously, oral treatment with plumieride (5, 10 and 20 mg/kg body weight/day for 30 days), restored all the parameters towards a normal level, remarkably. " 02/01/2004 - "Oral feeding of male rats with plumieride (15 mg/rat/day) for the period of 60 days did not cause any significant change in the body weight of treated rats. "
4.	Neoplasms (Cancer) 09/17/2004 - "The in vitro cytotoxicity of the plumieride analogues was determined in radiation-induced fibrosarcoma (RIF) tumor cells."
5.	Fibrosarcoma 09/17/2004 - "The in vitro cytotoxicity of the plumieride analogues was determined in radiation-induced fibrosarcoma (RIF) tumor cells."