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transportan

a galparan (C107160) analog, useful as a carrier vector for hydrophilic molecule, therefore named transportan; amino acid sequence known

Also Known As:

Lys(13)-galparan

Networked: 12 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Langel, Ulo: 4 articles (01/2006 - 01/2004)
2.	Hansen, Mats: 2 articles (03/2010 - 10/2005)
3.	Saar, Külliki: 2 articles (03/2010 - 10/2005)
4.	Eiríksdóttir, Emelía: 2 articles (01/2006 - 10/2005)
5.	Jiang, Yang: 2 articles (10/2005 - 05/2005)
6.	Aguiar, Luísa: 1 article (02/2019)
7.	Gomes, Paula: 1 article (02/2019)
8.	Machado, Marta: 1 article (02/2019)
9.	Prudêncio, Miguel: 1 article (02/2019)
10.	Sanches-Vaz, Margarida: 1 article (02/2019)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 01/01/2018 - "Label-Free Confocal Raman Mapping of Transportan in Melanoma Cells." 01/01/1998 - "In Bowes' melanoma cells, transportan first localizes in the outer membrane and cytoplasmatic membrane structures. " 01/01/2018 - "In this work, we employed confocal Raman microscopy (CRM) and atomic force microscopy (AFM) to study the infiltration and physiological effects of the amphipathic CPP transportan (Tp) on the metastatic melanoma cell line SK-Mel-2. " 05/20/2005 - "We analyse and compare the uptake of the fluorescein-labeled CPPs, transportan, TP10, penetratin and pVEC in Bowes human melanoma cells and Nicotiana tabacum cultivar (cv.) SR-1 protoplasts (plant cells without cell wall). "
2.	Neoplasms (Cancer) 01/01/2023 - "Here, we use fluorescence microscopy methods to analyze the interactions between the multifunctional peptide Transportan 10 (TP10) and the giant plasma membrane vesicles (GPMVs) derived from cancer cells. " 10/01/2005 - "Therefore, we investigated membrane toxicity of five peptides with well-documented cell-penetrating properties, pAntp(43-58), pTAT(48-60), pVEC(615-632), model amphipathic peptide (MAP), and transportan 10, on two human cancer cell lines, K562 (erythroleukemia) and MDA-MB-231 (breast cancer), as well as on immortalized aortic endothelial cells. "
3.	Breast Neoplasms (Breast Cancer) 04/03/2014 - "LXXLL peptide converts transportan 10 to a potent inducer of apoptosis in breast cancer cells." 10/01/2005 - "Therefore, we investigated membrane toxicity of five peptides with well-documented cell-penetrating properties, pAntp(43-58), pTAT(48-60), pVEC(615-632), model amphipathic peptide (MAP), and transportan 10, on two human cancer cell lines, K562 (erythroleukemia) and MDA-MB-231 (breast cancer), as well as on immortalized aortic endothelial cells. " 04/03/2014 - "We examined the effects of a peptide that contains the LXXLL-motif of the human SRC-1 nuclear receptor box 1 linked to the cell-penetrating transportan 10 (TP10), hereafter referred to as TP10-SRC1LXXLL, on proliferation and estrogen-mediated transcription of breast cancer cells in vitro. "
4.	Colorectal Neoplasms (Colorectal Cancer) 01/01/2014 - "Transportan (TP) and its shorter analog transportan 10 (TP10) are among the best studied CPPs, however, their effects on viability of and cargo introduction into colorectal cancer (CRC) cells have yet not been investigated. " 01/01/2014 - "Protein and siRNA delivery by transportan and transportan 10 into colorectal cancer cell lines."
5.	Malaria 02/01/2019 - "Coupling the cell-penetrating peptides transportan and transportan 10 to primaquine enhances its activity against liver-stage malaria parasites."

Related Drugs and Biologics

1.	6-chloro-2-(1-piperazinyl)pyrazine (CPP)
2.	Peptides (Polypeptides)
3.	Cell-Penetrating Peptides
4.	penetratin
5.	Small Interfering RNA (siRNA)
6.	Fluoroquinolones
7.	5' Untranslated Regions (5' UTR)
8.	Fluorescein (Funduscein)
9.	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)
10.	Messenger RNA (mRNA)

Related Therapies and Procedures

1.	Cell Transplantation
2.	Therapeutics