epoxyscillirosidin

1alpha,2alpha-isomer from Homeria pallida; structure in first source

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

1.	Poisoning 08/01/1997 - "The inhibition of cardiac Na,K-ATPase by 1 alpha,2 alpha-epoxyscillirosidin is the principal cause of poisoning of cattle by the tulip, Homeria pallida. " 03/01/2003 - "Aversion treatment with a combination of epoxyscillirosidin and lithium chloride together with a tulp-hexane extract, which served as identification factor for tulp, resulted in a significantly lower (P < 0.001) proportion of severe tulp poisoning. " 09/01/1995 - "In vivo effects of a novel calcium antagonist (R56865) against induced epoxyscillirosidin and tulp poisoning in sheep."
2.	Ventricular Tachycardia 09/01/1995 - "One of the epoxyscillirosidin sheep was treated while exhibiting paroxysmal ventricular tachycardia. "
3.	Tachycardia (Tachyarrhythmias) 09/01/1995 - "R56865 (Janssen Pharmaceutica, Pty Ltd), a novel Ca++ antagonist, was administered at the first distinct signs of cardiac disturbances in the sheep given epoxyscillirosidin and after development of tachycardia and dyspnoea in those that received plant material. "

1.	Lithium Chloride
2.	Hexanes
3.	Calcium
4.	Adenosine Triphosphatases (ATPase)
5.	R 56865