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E coli ispH protein

an essential that controls stringent response; involved in penicillin tolerance; regulates activity of ppGpp synthetase (RelA); also involved in the nonmevalonate (DOXP) pathway; amino acid sequence in first source; do not confuse with LytB protein from Streptococcus pneumoniae which is a murein hydrolase; converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate intoisopentenyl diphosphate plus dimethylallyl diphosphate
Also Known As:
ispH protein, E coli; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, E coli; yaaE protein, E coli
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