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caspase-activated deoxyribonuclease

degrades DNA during apoptosis, inhibited by ICAD (inhibitor of CAD); a protein of 343 amino acids carrying a nuclear localization signal; amino acid sequence in first source
Also Known As:
CAD enzyme; caspase-activated DNase
Networked: 31 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Singh, Sukh Mahendra: 5 articles (12/2013 - 11/2007)
2. Salimath, Bharathi P: 3 articles (08/2007 - 05/2005)
3. Singh, Vivek: 2 articles (12/2013 - 11/2007)
4. Vishvakarma, Naveen Kumar: 2 articles (12/2013 - 10/2011)
5. Jiang, Ding-Sheng: 1 article (04/2015)
6. Li, Hongliang: 1 article (04/2015)
7. Huang, Kun: 1 article (04/2015)
8. Huang, Kai: 1 article (04/2015)
9. Zhang, Xiao-Dong: 1 article (04/2015)
10. Gao, Lu: 1 article (04/2015)

Related Diseases

1. Nephritis
2. Neoplasms (Cancer)
3. Lymphoma (Lymphomas)
4. Ischemia
5. Huntington Disease (Huntington's Disease)

Related Drugs and Biologics

1. endonuclease G
2. Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
3. Macrophage Colony-Stimulating Factor
4. Caspase 3 (Caspase-3)
5. DNA (Deoxyribonucleic Acid)
6. Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
7. Proteins (Proteins, Gene)
8. NF-kappa B (NF-kB)
9. Nucleosomes (Nucleosome)
10. Interleukin-2 (IL2)

Related Therapies and Procedures

1. Intranasal Administration