|1.||Rawat, Diwan S: 1 article (08/2008)|
|2.||Joshi, Penny: 1 article (08/2008)|
|3.||Sharma, Mukul: 1 article (08/2008)|
|4.||Singh, Ram: 1 article (08/2008)|
|5.||Meyer, Arndt: 1 article (12/2005)|
|6.||Andreu, José M: 1 article (12/2005)|
|7.||Paterson, Ian: 1 article (12/2005)|
|8.||Barasoain, Isabel: 1 article (12/2005)|
|9.||Buey, Rubén M: 1 article (12/2005)|
|10.||Giannakakou, Paraskevi: 1 article (12/2005)|
03/15/1998 - "Eleutherobin is a novel natural product isolated from a marine soft coral that is extremely potent for inducing tubulin polymerization in vitro and is cytotoxic for cancer cells with an IC50 similar to that of paclitaxel. "
08/01/2008 - "Didemnin was the first marine peptide that entered in human clinical trials in US for the treatment of cancer and other compounds such as dolastatin-10, soblidotin, didemnin B, ecteinascidin 743, girolline, aplidine, cryptophycins (also arenastatin A), bryostatin 1, ILX 651, kahalalide F, E7389, discodermolide, ES-285 (spisulosine), HTI-286 (hemiasterlin derivative), squalamine, KRN-7000, vitilevuamide, Laulimalide, Curacin A, diazonamide, peloruside A, eleutherobin, sarcodictyin, thiocoraline, salicylihalimides A, ascididemnin, CGX-1160, CGX-1007dictyodendrins, GTS-21 (aka DMBX), manoalide, IPL-576,092 (aka HMR-4011A) have entered in the clinical trials. "
03/15/1998 - "Human colon carcinoma cells exposed to eleutherobin contain multiple micronuclei and microtubule bundles, and they arrest in mitosis, depending on concentration, cell line, and length of exposure. "
12/01/2005 - "The binding constants of epothilones, eleutherobin, discodermolide, sarcodictyins, 3,17beta-diacetoxy-2-ethoxy-6-oxo-B-homo-estra-1,3,5(10)-triene, and dictyostatin to the paclitaxel site; the critical concentrations of ligand-induced assembly; and their cytotoxicity in carcinoma cells have been measured, and correlations between these parameters have been determined. "