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mutein 3
differs from native TNF-alpha in its N-terminal sequence
Also Known As:
mutein III
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Glycoconjugates: 1353
Glycoproteins: 24834
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Amino Acids, Peptides, and Proteins: 1
Proteins: 484843
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Monokines: 214
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Tumor Necrosis Factors: 152
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Glycoproteins: 24834
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Blood Proteins: 12459
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Peptides: 82426
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Monokines: 214
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Tumor Necrosis Factors: 152
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Biological Factors: 2472
Intercellular Signaling Peptides and Proteins: 29768
Cytokines: 164289
Monokines: 214
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Tumor Necrosis Factors: 152
Tumor Necrosis Factor-alpha: 62515
mutein 3: 1
Related Diseases
1.
Carcinoma (Carcinomatosis)
03/01/1993 - "
We observed binding to the p75 TNF receptor on Jijoye Burkitt lymphoma cells with native TNF-alpha and mutein III alone, whereas the p55 TNF receptor on the human epithelioid carcinoma cell line HeLa bound TNF-alpha, mutein III and mutein V. Muteins IV and VI failed to recognize either TNF receptor.
"
2.
Burkitt Lymphoma (Burkitt's Lymphoma)
03/01/1993 - "
We observed binding to the p75 TNF receptor on Jijoye Burkitt lymphoma cells with native TNF-alpha and mutein III alone, whereas the p55 TNF receptor on the human epithelioid carcinoma cell line HeLa bound TNF-alpha, mutein III and mutein V. Muteins IV and VI failed to recognize either TNF receptor.
"
Related Drugs and Biologics
1.
Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)
2.
Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.
mutein 5