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EM 343

an anti-estrogen

Also Known As:

7-hydroxy-3-(4'-hydroxyphenyl)-4-methyl-2-(4''-2''-piperidinoethoxy)phenyl-2H-benzopyran; EM-343

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - EM 343: 1
  - Piperidines: 17
    - EM 343: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - EM 343: 1

Related Diseases

1.	Neoplasms (Cancer) 11/27/1997 - "At the low daily dose of 5 microg, EM-343 administered subcutaneously for 6 months completely blocked the stimulatory effect of endogenous estrogens on the growth of ZR-75-1 and MCF-7 tumors implanted in nude mice. " 11/27/1997 - "The effects of the novel anti-estrogen EM-343 on the growth of 2 hormone-responsive human breast cancer tumors have been examined in athymic nude mice. "
2.	Breast Neoplasms (Breast Cancer) 11/27/1997 - "Our data show the pure anti-estrogenic properties of EM-343 and its high potency as an inhibitor of growth of human ZR-75-1 and MCF-7 breast tumors in nude mice." 11/27/1997 - "The effects of the novel anti-estrogen EM-343 on the growth of 2 hormone-responsive human breast cancer tumors have been examined in athymic nude mice. "

Related Drugs and Biologics

1.	Hormones (Hormone)
2.	Estrogens (Estrogen)