4C7 monoclonal antibody

a commercially available anti-CD5 MAb, used for the immunohistochemical detection of CD5 on paraffin sections

Also Known As:

4C7 antibody; MAb 4C7; monoclonal antibody 4C7

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        4C7 monoclonal antibody: 4
    - Immunoproteins: 43
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        4C7 monoclonal antibody: 4
  - Globulins: 3062
    - Serum Globulins: 553
      - Immunoglobulins: 30480
        Antibodies: 133716
        Monoclonal Antibodies: 56412
        4C7 monoclonal antibody: 4

Experts

1.	Ingerpuu, Sulev: 1 article (01/2013)
2.	Ishikawa, Taichi: 1 article (01/2013)
3.	Javed, Fawad: 1 article (01/2013)
4.	Juronen, Erkki: 1 article (01/2013)
5.	Oikawa, Yuko: 1 article (01/2013)
6.	Omrani, Shahin: 1 article (01/2013)
7.	Patarroyo, Manuel: 1 article (01/2013)
8.	Virtanen, Ismo: 1 article (01/2013)
9.	Wondimu, Zenebech: 1 article (01/2013)

Related Diseases

1.	Carcinoma (Carcinomatosis) 01/01/2013 - "Of greatest interest, mAb 8G9, but not any other antibody, strongly inhibited α3β1/α6β1 integrin-mediated adhesion and migration of glioma, melanoma, and carcinoma cells on laminin-511 and, together with mAb 4C7, on laminin-521. " 05/01/1985 - "One epitope, identified by Mab 4C7, is expressed only on mucinous carcinoma, endometrioid carcinoma, and mesonephroid carcinoma, while the epitope, identified by Mab 3C2, appears only on serous and endometrioid carcinoma."
2.	Endometrioid Carcinoma 05/01/1985 - "One epitope, identified by Mab 4C7, is expressed only on mucinous carcinoma, endometrioid carcinoma, and mesonephroid carcinoma, while the epitope, identified by Mab 3C2, appears only on serous and endometrioid carcinoma."
3.	B-Cell Lymphoma (Lymphoma, B Cell) 12/01/1997 - "Therefore, we tested the utility of monoclonal antibody (MAb) 4C7 to detect CD5 on paraffin sections of 22 cases with low-grade B-cell lymphomas and 4 cases with high-grade B-cell lymphomas and compared the results with CD5 detection by analysis of fresh tissue with a fluorescent-activated cell sorting (FACS). "
4.	Muscular Dystrophies (Muscular Dystrophy) 11/07/1997 - "Laminin alpha1 has been reported to localize to human fetal muscle and to be induced in muscular dystrophies based on immunohistochemistry with the monoclonal antibody 4C7, suggested to recognize the human laminin alpha1 chain. "
5.	Melanoma (Melanoma, Malignant) 01/01/2013 - "Of greatest interest, mAb 8G9, but not any other antibody, strongly inhibited α3β1/α6β1 integrin-mediated adhesion and migration of glioma, melanoma, and carcinoma cells on laminin-511 and, together with mAb 4C7, on laminin-521. "

Related Drugs and Biologics

1.	Integrins
2.	Paraffin
3.	Epitopes
4.	Monoclonal Antibodies
5.	laminin A