|1.||Sato, Hiroshi: 1 article (12/2003)|
|2.||Kinoshita, Yoshikazu: 1 article (12/2003)|
|3.||Kazumori, Hideaki: 1 article (12/2003)|
|4.||Ortega-Cava, Cesar Francisco: 1 article (12/2003)|
|5.||Yuki, Mika: 1 article (12/2003)|
|6.||Adachi, Kyoichi: 1 article (12/2003)|
|7.||Rumi, Mohammad Azharul Karim: 1 article (12/2003)|
|8.||Ishihara, Shunji: 1 article (12/2003)|
|9.||Ishihara, Yasunobu: 1 article (12/2003)|
|10.||Ono, Masahiro: 1 article (12/2003)|
04/01/2000 - "Similarly to the Heidenhain pouch model, even in the gastric fistula (GF) model, S-0509 significantly inhibited pentagastrin-stimulated gastric acid secretion, yet the drug had no effect on carbachol-stimulated secretion. "
05/01/1999 - "In chronic gastric fistula rats, S-0509 also significantly inhibited pentagastrin- and carbachol-stimulated gastric acid secretion in a dose-related manner, but had no effect on histamine-stimulated secretion. "
05/01/1999 - "Antisecretory and ulcer healing effects of S-0509, a novel CCK-B/gastrin receptor antagonist, in rats."
05/01/1999 - "A two-week treatment with S-0509 markedly enhanced the spontaneous healing of acetic acid ulcers and prevented the delay in ulcer healing caused by indomethacin. "
05/01/1999 - "The effects of a novel CCK-B/gastrin receptor antagonist, S-0509, on gastric acid secretion and the healing of acetic acid ulcers in rats were examined. "
05/01/1999 - "In addition, S-0509 markedly inhibited pentagastrin- and carbachol-stimulated acid secretion in both normal rats and rats with ulcers, but failed to inhibit histamine-stimulated secretions. "
|3.||Stomach Ulcer (Gastric Ulcer)
|4.||Peptic Ulcer (Peptic Ulcers)
12/01/2003 - "Coadministration of S-0509 with omeprazole or gastrin almost completely inhibited the omeprazole- and gastrin-induced changes in gastric mucosa, including mucosal thickening and ECL hyperplasia. "
12/01/2003 - "In summary, we have found that a newly developed gastrin receptor antagonist, S-0509, inhibits omeprazole- and gastrin-induced mucosal hyperplasia, especially ECL-cell hyperplasia, in rats."
|1.||Cholecystokinin B Receptor
|4.||Acetic Acid (Vinegar)
|7.||Histamine (Histamine Dihydrochloride)