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ampullosporin

a 15-membered peptaibol-type antibiotic from Sepedonium ampullosporum; structure given in first source

Also Known As:

ampullosporin A

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptaibols: 21
    - ampullosporin: 3

Experts

1.	Gräfe, Udo: 2 articles (11/2003 - 06/2002)
2.	Imhof, Diana: 2 articles (11/2003 - 06/2002)
3.	Kronen, Matthias: 2 articles (11/2003 - 06/2002)
4.	Nguyen, Hoai-Huong: 2 articles (11/2003 - 06/2002)
5.	Reissmann, Siegmund: 2 articles (11/2003 - 06/2002)
6.	Gera, Lajos: 1 article (06/2002)
7.	Härtl, Albert: 1 article (06/2002)
8.	Schlegel, Brigitte: 1 article (06/2002)

Related Diseases

1.	Hypothermia 09/01/1997 - "Ampullosporin displays narrow-spectrum antibacterial and antifungal activity, induces pigment formation by Phoma destructiva, causes hypothermia and decreased spontaneous locomotor activity in mice in dosages > 1 mg/kg." 11/01/2003 - "Ampullosporin A (AmpA), a 15mer peptalbol containing seven Aib residues is able to induce pigmentation on Phoma destructiva and hypothermia in mice, as well as to exhibit a neuroleptic effect. "
2.	Tics (Tic) 06/20/2002 - "Similarly, the ampullosporin A analogues with N-terminal aromatic amino acid residues, such as D-Trp and Tic, also have high potency for pigment formation. "

Related Drugs and Biologics

1.	Aromatic Amino Acids (Aromatic Amino Acid)
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3.	Antipsychotic Agents (Antipsychotics)