|1.||Löscher, W: 1 article (05/2001)|
|2.||Bartsch, R: 1 article (05/2001)|
|3.||Hönack, D: 1 article (05/2001)|
|4.||Tober, C: 1 article (05/2001)|
05/01/2001 - "This study demonstrates that AWD 140-190 has anticonvulsant effects in the amygdala kindling model in rats, suggesting that the substance is particularly effective against partial seizures. "
05/01/2001 - "Prolonged treatment with AWD 140-190 during kindling acquisition did not prevent kindling, but significantly retarded the development of fully kindled seizures during the treatment. "
05/01/2001 - "AWD 140-190 exerted potent anticonvulsant activity against focal seizures. "
05/01/2001 - "Evaluation of the effect of the new anticonvulsant drug, AWD 140-190 [4-(p-bromophenyl)-3-morpholino-1H-pyrrole-2-carboxylic acid methyl ester] on focally induced seizures and on epileptogenesis in the kindling model. "
05/01/2001 - "After intraperitoneal and oral administration in fully kindled rats, the substance dose-dependently increased the threshold for induction of afterdischarges starting at 15 mg/kg. AWD 140-190 only weakly influenced the seizure severity of the animals after stimulation at the elevated afterdischarge threshold current. "
03/01/1999 - "This pronounced use dependent effect of AWD 140-190 may be the reason for the superior tolerability and anticonvulsant activity in experimental models of epilepsy."
07/01/1997 - "The anticonvulsant activity of the novel drug AWD 140-190 (4-(p-bromophenyl)-3-morpholino-1H-pyrrole-2-carboxylic acid methyl ester) was evaluated in animal models of epileptic seizures. "
|3.||Partial Epilepsies (Epilepsy, Partial)