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KT 7595
inhibits farnesyl protein transferase; structure given in first source
Also Known As:
KT-7595; KT7595
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Indoles: 200
Gliotoxin: 171
KT 7595: 1
Biological Factors: 2472
Biological Toxins: 20
Mycotoxins: 1745
Gliotoxin: 171
KT 7595: 1
Related Diseases
1.
Hepatocellular Carcinoma (Hepatoma)
01/01/1997 - "
We have tested the effect of the FPTase inhibitors manumycin, an analogue of farnesyl diphosphate, and KT7595, a gliotoxin derivative, on Ras farnesylation, DNA synthesis and the anchorage-dependent and -independent growth of human colon carcinoma (LoVo), hepatoma (Mahlavu and PLC/PRF/5) and gastric carcinoma (KATO III).
"
2.
Carcinoma (Carcinomatosis)
01/01/1997 - "
We have tested the effect of the FPTase inhibitors manumycin, an analogue of farnesyl diphosphate, and KT7595, a gliotoxin derivative, on Ras farnesylation, DNA synthesis and the anchorage-dependent and -independent growth of human colon carcinoma (LoVo), hepatoma (Mahlavu and PLC/PRF/5) and gastric carcinoma (KATO III).
"
Related Drugs and Biologics
1.
Gliotoxin
2.
DNA (Deoxyribonucleic Acid)
3.
manumycin
4.
farnesyl pyrophosphate (farnesyl diphosphate)