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21-hydroxy-6,19-oxidoprogesterone

structure in first source

Also Known As:

21-hydroxy-6,19-epoxyprogesterone; 21OH-6,19OP; 21OH-6OP

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Progesterone: 12723
        21-hydroxy-6,19-oxidoprogesterone: 1
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Gonadal Hormones: 716
    - Gonadal Steroid Hormones: 7657
      - Progesterone Congeners: 320
        Progesterone: 12723
        21-hydroxy-6,19-oxidoprogesterone: 1
    - Corpus Luteum Hormones: 1
      - Progesterone: 12723
        21-hydroxy-6,19-oxidoprogesterone: 1

Experts

1.	Bal de Kier Joffé, Elisa: 1 article (06/2014)
2.	Burton, Gerardo: 1 article (06/2014)
3.	Dansey, M Virginia: 1 article (06/2014)
4.	Español, Alejandro: 1 article (06/2014)
5.	Orqueda, Andres J: 1 article (06/2014)
6.	Pecci, Adali: 1 article (06/2014)
7.	Sales, M Elena: 1 article (06/2014)
8.	Veleiro, Adriana S: 1 article (06/2014)

Related Diseases

1.	Neoplasms (Cancer) 06/15/2014 - "However, contrary to dexamethasone (DEX), 21OH-6,19OP neither reverts the paclitaxel-induced caspase-3 activity, nor induces the anti-apoptotic Bcl-X(L) gene expression in murine tumor mammary epithelial cells; and importantly, it lacks GCs-associated chemoresistance in a mouse mammary tumor model. "
2.	Breast Neoplasms (Breast Cancer) 06/15/2014 - "The rigid steroid 21-hydroxy-6,19-epoxyprogesterone (21OH-6,19OP) is a dissociated glucocorticoid receptor modulator potentially useful as a novel coadjuvant in breast cancer chemotherapy."

Related Drugs and Biologics

1.	Caspase 3 (Caspase-3)
2.	Paclitaxel (Taxol)
3.	Steroids
4.	Glucocorticoid Receptors (Glucocorticoid Receptor)
5.	Dexamethasone (Maxidex)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)