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A 131701

uroselective alpha(1A) adrenoceptor antagonist; used for treating benign prostatic hyperplasia; structure in first source

Also Known As:

3-(2-(6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz(e)isoindol-2-yl)ethyl)pyrido(3',4'-4,5)thieno(3,2-d)pyrimidine-2,4(1H,3H)-dione; A-131701

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - Pyrimidinones: 71
      - A 131701: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoindoles: 18
      - A 131701: 2

Related Diseases

1.

Prostatic Hyperplasia (Benign Prostatic Hyperplasia)

05/01/1998 - "Therefore, A-131701 should have clinical utility in the pharmacotherapy of benign prostatic hyperplasia."
09/26/1997 - "Synthesis and pharmacological characterization of 3-[2-((3aR,9bR)-cis-6-methoxy-2,3,3a,4,5,9b-hexahydro-1H-benz[e] isoindol-2-yl)ethyl]pyrido-[3',4':4,5]thieno[3,2-d]pyrimidine-2,4 (1H,3H)-dione (A-131701): a uroselective alpha 1A adrenoceptor antagonist for the symptomatic treatment of benign prostatic hyperplasia."

Related Drugs and Biologics

1.	Adrenergic Receptors (Adrenergic Receptor)
2.	pyrimidine

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)