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chlorambucil-taurocholate
Also Known As:
3H-chlorambucil-taurocholate; S 2676; S2676
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Halogenated Hydrocarbons: 42
Mustard Compounds: 3
Nitrogen Mustard Compounds: 2
Chlorambucil: 1430
chlorambucil-taurocholate: 1
Acyclic Hydrocarbons
Alkanes: 241
Alkanesulfonic Acids
Taurine: 3452
Taurocholic Acid: 1216
chlorambucil-taurocholate: 1
Sulfur Compounds: 278
Sulfur Acids
Sulfonic Acids: 1605
Alkanesulfonic Acids
Taurine: 3452
Taurocholic Acid: 1216
chlorambucil-taurocholate: 1
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Bile Acids and Salts: 11432
Cholic Acids: 14
Taurocholic Acid: 1216
chlorambucil-taurocholate: 1
Cholanes
Cholic Acids: 14
Taurocholic Acid: 1216
chlorambucil-taurocholate: 1
Related Diseases
1.
Hepatocellular Carcinoma (Hepatoma)
10/01/1997 - "
Expression of hepatocellular carcinoma mRNA in oocytes resulted in mainly Na(+)-dependent uptake of chlorambucil-taurocholate.
"
10/01/1997 - "
Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas.
"
10/01/1997 - "
Because NTCP mediates high-affinity uptake of chlorambucil-taurocholate, targeting of cytostatic bile acids to hepatocellular carcinomas could become a feasible therapeutic strategy.
"
2.
Carcinoma (Carcinomatosis)
10/01/1997 - "
Uptake of the cytostatic drug [3H]-chlorambucil-taurocholate (S2676) was measured in Xenopus laevis oocytes injected with total messenger RNA (mRNA) from the carcinomas or peritumor tissue or with complementary RNA encoding the NTCP or the organic anion-transporting polypeptide (OATP) of human liver.
"
Related Drugs and Biologics
1.
chlorambucil-taurocholate
2.
Cytostatic Agents
3.
Complementary RNA (cRNA)
4.
Messenger RNA (mRNA)
5.
Peptides (Polypeptides)
6.
Bile Acids and Salts (Bile Acids)
7.
Anions