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AL 3789

structure given in first source

Also Known As:

AL-3789

Networked: 1 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Hydrocortisone: 24422
        AL 3789: 1
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Adrenal Cortex Hormones: 62914
    - Hydroxycorticosteroids: 7
      - 17-Hydroxycorticosteroids: 179
        Hydrocortisone: 24422
        AL 3789: 1
      - 11-Hydroxycorticosteroids: 56
        Hydrocortisone: 24422
        AL 3789: 1

Related Diseases

1.

Corneal Neovascularization

09/01/1997 - "All tested formulations, except the vehicle and the 0.01% AL-3789 preparation, significantly inhibited corneal neovascularization and other lipopolysaccharide-induced responses in the various treatment protocols employed. "
09/01/1997 - "The antiangiogenic steroid AL-3789 may be a therapeutically useful angiostatic agent for corneal neovascularization and potentially could be effective in other ocular neovascular diseases."
09/01/1997 - "To evaluate the antiangiogenic potential of topical ophthalmic formulations of the novel angiostatic steroids AL-3789 and AL-4940, using a rabbit model of corneal neovascularization. "

Related Drugs and Biologics

1.	Angiogenesis Inhibitors
2.	Steroids
3.	Lipopolysaccharides
4.	Anecortave