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proadrenomedullin (9-20)

a major endogenous biologically active peptide from porcine medulla; amino acid sequence given in first source

Also Known As:

PAMP(9-20); PAMP-12

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Peptide Hormones: 1347
    - Adrenomedullin: 1691
      - proadrenomedullin (9-20): 4
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Peptide Hormones: 1347
    - Adrenomedullin: 1691
      - proadrenomedullin (9-20): 4

Experts

1.	Arizmendi, Narcy: 1 article (12/2021)
2.	Che, Delu: 1 article (12/2021)
3.	Ding, Jie: 1 article (12/2021)
4.	Du, Xueshan: 1 article (12/2021)
5.	Eitzen, Gary: 1 article (12/2021)
6.	Geng, Songmei: 1 article (12/2021)
7.	Hou, Yajing: 1 article (12/2021)
8.	Jia, Tao: 1 article (12/2021)
9.	Kulka, Marianna: 1 article (12/2021)
10.	Kwan, Peter: 1 article (12/2021)

Related Diseases

1.	type 2C Congenital disorder of glycosylation 12/01/2021 - "It was found that FRKKW and WNKWAL are two motifs that activate human LAD2 cells similar to PAMP-12 controls. " 01/01/2022 - "We found that C9, but not its inactive analog C7, inhibited degranulation in RBL-2H3 cells stably expressing MRGPRX2 in response to SP, PAMP-12 and rocuronium with an IC50 value of ~300 nM. C9 also inhibited degranulation as measured by cell surface expression of CD63, CD107a and β-hexosaminidase release in LAD2 cells and human skin-derived MCs in response to SP but not the anaphylatoxin, C3a or FcϵRI-aggregation. "
2.	Hypersensitivity (Allergy) 12/01/2021 - "Due to the lack of direct available comparisons, the different types of sensitizing mediators released by the action of SP and PAMP(9-20) inducing pseudo-allergic reactions via MRGPRX2 are unclear. "
3.	Essential Hypertension 09/01/1999 - "Using a new, sensitive radioimmunoassay which recognizes the C-terminal region of PAMP-20 [PAMP(1-20)], we investigated the role of PAMP in patients with essential hypertension who had normal renal function, and whether PAMP-12 is present in humans. "

Related Drugs and Biologics

1.	Hexosaminidases (Hexosaminidase)
2.	Anaphylatoxins
3.	Rocuronium (Zemuron)
4.	Pathogen-Associated Molecular Pattern Molecules