Physostigmine

A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

Also Known As:

Eserine; Pyrrolo(2,3-b)indol-5-ol, 1,2,3,3a,8,8a- hexahydro- 1,3a,8- trimethyl- , methylcarbamate (ester), (3aS-cis)-

Pharmalogical Action Categories:

Cholinesterase Inhibitors
Miotics

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Carbamates: 945
      - Phenylcarbamates: 7
        Physostigmine: 939
Heterocyclic Compounds: 198
- Alkaloids: 5398
  - Indole Alkaloids: 200
    - Physostigmine: 939
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Indole Alkaloids: 200
        Physostigmine: 939
    - Indolizines: 3
      - Indolizidines: 2
        Indole Alkaloids: 200
        Physostigmine: 939

N(8)-norphysostigmine

Bio-Agent Context: Research Results