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marenostrin (pyrin)

gene MEFV is a candidate gene for familial Mediterranean fever; name marenostrin is derived from mare nostrum, Latin for Mediterranean sea; related to ret-finger protein & butyrophilin; amino acid sequence given in first source; a 95-aa pyrin homology region (also called PAAD, DAPIN, or Pyk domain) is a member of the 6-helix bundle death domain-fold superfamily that includes death domains, death effector domains, and caspase recruitment domains; GenBank Y14441; RefSeq NM_000243 (human), NM_019453 (mouse)
Also Known As:
pyrin; FMF protein, human; MEFV protein; MEFV protein, human; Marenostrin protein, human; Mediterranean fever protein, human; Mediterranean fever protein, mouse; Mefv protein, mouse; Pyrin protein, human; marenostrin protein, mouse; pyrin protein, mouse
Networked: 303 relevant articles (5 outcomes, 30 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kastner, Daniel L: 11 articles (03/2015 - 12/2002)
2. Chae, Jae Jin: 8 articles (03/2015 - 12/2002)
3. Núñez, Gabriel: 8 articles (03/2015 - 02/2003)
4. Taniguchi, Shun'ichiro: 7 articles (11/2015 - 05/2002)
5. Masters, Seth L: 7 articles (03/2015 - 01/2006)
6. Sagara, Junji: 6 articles (01/2015 - 05/2002)
7. Masumoto, Junya: 6 articles (01/2014 - 05/2002)
8. Aksentijevich, I: 6 articles (10/2011 - 06/2000)
9. Aksentijevich, Ivona: 6 articles (11/2010 - 12/2002)
10. Stehlik, Christian: 5 articles (10/2015 - 07/2003)

Related Diseases

1. Inflammation
2. Fever (Fevers)
3. Insulin Resistance
4. Familial Mediterranean Fever (Periodic Disease)
5. Infection

Related Drugs and Biologics

1. Leucine (L-Leucine)
2. rho-Associated Kinases
3. Leptin Receptors
4. STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)
5. Pro-Opiomelanocortin (Proopiomelanocortin)
6. Phosphotransferases (Kinase)
7. Neuropeptide Y
8. Anti-Bacterial Agents (Antibiotics)
9. marenostrin (pyrin)
10. Inflammasomes

Related Therapies and Procedures

1. Artificial Respiration (Mechanical Ventilation)
2. Lasers (Laser)
3. Hyperbaric Oxygenation
4. Renal Dialysis (Hemodialysis)