decysin

a disintegrin metalloproteinase from CD40-activated germinal center dendritic cells; amino acid sequence in first source; GenBank Y13323

Also Known As:

ADAM-like decysin 1 protein, human; ADAMDEC1 protein, human

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Peptide Hydrolases: 23957
      - Metalloproteases: 8276
        Metalloendopeptidases: 70
        ADAM Proteins: 24
        decysin: 5
Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - decysin: 5
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - ADAM Proteins: 24
      - decysin: 5

Experts

1.	Baek, Gain: 1 article (04/2022)
2.	Bartlett, Allison: 1 article (04/2022)
3.	Becker, Laren: 1 article (04/2022)
4.	Choi, Suck-Chei: 1 article (04/2022)
5.	Gottfried-Blackmore, Andres: 1 article (04/2022)
6.	Ha, Se Eun: 1 article (04/2022)
7.	Habtezion, Aida: 1 article (04/2022)
8.	Jin, Byungchang: 1 article (04/2022)
9.	Jorgensen, Brian G: 1 article (04/2022)
10.	Kim, Min-Seob: 1 article (04/2022)

Related Diseases

1.	Rupture 01/01/2005 - "Previous studies have shown that: (a) the rupture of chorioamniotic membranes is related to an imbalance between synthesis and degradation of collagen induced by the overexpression/activity of various matrix metalloproteinases (MMP); (b) during human labor and delivery the expression of prolactin receptors (PRL-R) increases in chorioamniotic membranes, decidua and placenta; (c) prolactin (PRL) can influence the synthesis of prostaglandins, the expression of some MMP (MMP-2, MMP-9 and decysin) and tissue inhibitors of MMP in general; (d) vitamin C deficiency induces the expression/activity of extracellular MMP and is considered a risk factor for PROM; and (e) vitamin C potentiates the dopamine-mediated inhibition of PRL in rats. "
2.	Ascorbic Acid Deficiency (Vitamin C Deficiency) 01/01/2005 - "Previous studies have shown that: (a) the rupture of chorioamniotic membranes is related to an imbalance between synthesis and degradation of collagen induced by the overexpression/activity of various matrix metalloproteinases (MMP); (b) during human labor and delivery the expression of prolactin receptors (PRL-R) increases in chorioamniotic membranes, decidua and placenta; (c) prolactin (PRL) can influence the synthesis of prostaglandins, the expression of some MMP (MMP-2, MMP-9 and decysin) and tissue inhibitors of MMP in general; (d) vitamin C deficiency induces the expression/activity of extracellular MMP and is considered a risk factor for PROM; and (e) vitamin C potentiates the dopamine-mediated inhibition of PRL in rats. "
3.	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 04/30/2022 - "Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα+ Cells Is a New Marker for Inflammatory Bowel Disease."
4.	Neoplasms (Cancer) 09/01/2012 - "The ADAM-like decysin 1 (ADAMDEC1) is a member of a disintegrin and metalloprotease (ADAM) family which correlates with tumor progression and aggressive behavior. "
5.	Necrosis 12/01/2003 - "In immature DC decysin mRNA was absent, even after induction of the terminal differentiation of DC by CD40L or tumour necrosis factor-alpha (TNF-alpha). "

Related Drugs and Biologics

1.	Matrix Metalloproteinases (MMPs)
2.	Prolactin Receptors (Prolactin Receptor)
3.	Prostaglandins
4.	Prolactin
5.	Dopamine (Intropin)
6.	Collagen
7.	Ascorbic Acid (Vitamin C)
8.	Metalloproteases (Metalloproteinases)
9.	CD40 Ligand (CD40L)
10.	Disintegrins