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DNA synthesome

a replication-competent multiprotein from human leukemia cell line HL-60; contains DNA polymerases alpha and delta, DNA primase, PCNA, replication factor C, replication protein A and DNA topoisomerases I and II
Also Known As:
DNA replisome; multiprotein DNA replication complex; multiprotein replication complex
Networked: 9 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1. Malkas, Linda H: 2 articles (04/2009 - 07/2005)
2. Hickey, Robert J: 2 articles (04/2009 - 07/2005)
3. Dai, Heqiao: 1 article (04/2009)
4. Liu, Jianying: 1 article (04/2009)
5. Sandoval, John A: 1 article (07/2005)
6. Jiang, H Y: 1 article (01/2000)
7. Malkas, L H: 1 article (01/2000)
8. Abdel-Aziz, W: 1 article (01/2000)
9. Hickey, R J: 1 article (01/2000)

Related Diseases

1. Breast Neoplasms (Breast Cancer)
2. Leukemia
3. Neoplasms (Cancer)
4. Carcinoma (Carcinomatosis)

Related Drugs and Biologics

1. DNA (Deoxyribonucleic Acid)
2. Cytarabine (Cytosar-U)
3. DNA synthesome
4. Replication Protein C (Replication Factor C)
5. Replication Protein A
6. DNA Topoisomerases
7. DNA Primase (Primase)
8. Proliferating Cell Nuclear Antigen (PCNA)
9. Proteins (Proteins, Gene)
10. Viral DNA

Related Therapies and Procedures

1. Heterologous Transplantation (Xenotransplantation)