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TER 286 (TLK286)

a glutathione-based glutathione S-transferase-activated cytotoxin; TLK-286 is the ((R)-(-))-isomer
Also Known As:
TLK286; N-(3-((2-((bis(bis(2-chloroethyl)amino)phosphinyl)oxy)ethyl)sulfonyl)-N-glutamyl-alanyl)-2-phenyl-glycine; TER-286; TER286; TLK 286; TLK-286; Telcyta; canfosfamide HCl; gamma-glutamyl-alpha-amino-beta-(2-ethyl-N,N,N',N'-tetrakis(2-chloroethyl)phosphorodiamidate)sulfonylpropionyl-(R)-(-) phenylglycine
Networked: 15 relevant articles (2 outcomes, 6 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Tew, Kenneth D: 2 articles (08/2005 - 10/2002)
2. Fernandes, Pedro Alexandrino: 1 article (11/2013)
3. Mannervik, Bengt: 1 article (11/2013)
4. Dourado, Daniel F A R: 1 article (11/2013)
5. Ramos, Maria João: 1 article (11/2013)
6. Gargoum, F: 1 article (01/2010)
7. Kennedy, B: 1 article (01/2010)
8. Bystricky, B: 1 article (01/2010)
9. Curran, D R: 1 article (01/2010)
10. O'Connor, T M: 1 article (01/2010)

Related Diseases

1. Lung Neoplasms (Lung Cancer)
2. Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
3. Carcinoma (Carcinomatosis)
4. Ovarian Neoplasms (Ovarian Cancer)
5. Neoplasms (Cancer)

Related Drugs and Biologics

1. TER 286 (TLK286)
2. Platinum
3. Glutathione (Reduced Glutathione)
4. Taxoids
5. Anthracyclines
6. Paclitaxel (Taxol)
7. Glutathione Transferase (Glutathione S-Transferase)
8. Topotecan (Hycamtin)
9. Carboplatin (JM8)
10. pegylated liposomal doxorubicin

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Stents