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methyl 21- acetyloxy- 3,20- dioxo- 11,17- dihydroxy- 9- fluoro- 1,4- pregnadiene- 16- carboxylate
structure in first source
Also Known As:
FP16CMAc
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Pregnanes: 9
Pregnadienes
Pregnadienediols
methyl 21-acetyloxy-3,20-dioxo-11,17-dihydroxy-9-fluoro-1,4-pregnadiene-16-carboxylate: 2
Related Diseases
1.
Inflammation (Inflammations)
12/01/1998 - "
In continuing efforts to synthesize potent, anti-inflammatory steroids devoid of systemic side effects, methyl 9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-3,20-dioxo-pregna-1,4-diene-16 alpha-carboxylate (FP16CM) and its 21-acetate derivative (FP16CMAc) were recently synthesized and screened in animal models of inflammation.
"
2.
Edema (Dropsy)
06/01/1997 - "
From these dose-response profiles, the following ID50 values (nmol resulting in a 50% reduction of edema) were calculated: 817, 540, 266, and 67 for hydrocortisone (HC), prednisolone (P), FP16CM, and FP16CMAc, respectively.
"
Related Drugs and Biologics
1.
methyl 3,20- dioxo- 9- fluoro- 11,17,21- trihydroxy- 1,4- pregnadiene- 16- carboxylate
2.
Steroids
3.
Prednisolone (Predate)
4.
Hydrocortisone (Cortisol)