MDL 74721

structure in first source

Also Known As:

7-(dipropylamino)-5,6,7,8-tetrahydro-N-methyl-1-naphthalenemethanesulfonamide 2-butanedioate; MDL 74,721; MDL 74,721G; MDL-74,721; MDL-74,721G; MDL-74721

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

Migraine Disorders (Migraine)

10/08/1997 - "In conclusion, MDL 74,721 demonstrates a preclinical profile consistent with anti-migraine efficacy. "
10/08/1997 - "MDL 74,721 (R)-2-(N1,N1-dipropylamino)-8-methylaminosulfonylmethyl-1,2,3,4-te trahydronaphthalene, a sulfonamidotetralin, has been found to exhibit a 10,000-fold greater potency in neurogenic versus vascular models of migraine. "
10/08/1997 - "The selectivity of MDL 74,721 in models of neurogenic versus vascular components of migraine."
04/01/1997 - "MDL 74,721 (I), sumatriptan(II) and naratriptan(III) are new 5-HT1-like agonists that have potential as a novel treatment for migraine. "

Related Drugs and Biologics

1.	Sumatriptan (Imigran)
2.	naratriptan