|1.||Hartmann, Arndt: 4 articles (10/2015 - 04/2004)|
|2.||Shimono, Akihiko: 4 articles (08/2015 - 07/2010)|
|3.||Hirata, Hiroshi: 4 articles (06/2010 - 08/2008)|
|4.||Dahiya, Rajvir: 4 articles (06/2010 - 08/2008)|
|5.||Chang, Ching-Jin: 4 articles (11/2006 - 05/2003)|
|6.||Lee, Jia-Lin: 4 articles (11/2006 - 05/2003)|
|7.||Lin, Chung-Tien: 4 articles (11/2006 - 05/2003)|
|8.||Stoehr, Robert: 3 articles (10/2015 - 04/2004)|
|9.||Arfuso, Frank: 3 articles (01/2015 - 01/2012)|
|10.||Wang, Rui: 3 articles (12/2014 - 01/2011)|
|1.||Breast Neoplasms (Breast Cancer)
01/01/2012 - "We showed here that Wnt5a activated Dvl2, Daam1 and RhoA, and promoted migration of breast cancer cells, which was, however, abolished by Secreted Frizzled-related protein 2 (sFRP2) pretreatment. "
01/01/2011 - "Secreted frizzled-related protein 1 (SFRP1) antagonizes this pathway and loss of SFRP1 expression is frequently observed in breast tumors and breast cancer cell lines. "
01/01/2009 - "Moreover, many breast tumors show hypermethylation of the secreted Frizzled-related protein 1 (sFRP1) promoter region, causing low expression of this WNT antagonist. "
01/01/2007 - "Most breast tumors show hypermethylation of the promoter region of secreted Frizzled-related protein 1 (sFRP1), a negative WNT pathway regulator, leading to downregulation of its expression. "
06/08/2006 - "The gene for secreted frizzled-related protein 1 (SFRP1) encodes a soluble Wnt antagonist and is located in a chromosomal region (8p22-p12) that is often deleted in breast cancer. "
11/07/2014 - "Secreted Frizzled-related protein 1 (Sfrp1) regulates the progression of renal fibrosis in a mouse model of obstructive nephropathy."
03/15/2014 - "The failing hamster heart exhibits marked fibrosis and increased expression of secreted Frizzled-related protein 2 (sFRP2) amenable to reversal by mesenchymal stem cell (MSC) therapy. "
11/01/2010 - "Secreted frizzled related protein 4 reduces fibrosis scar size and ameliorates cardiac function after ischemic injury."
12/07/2010 - "Exogenously administered secreted frizzled related protein 2 (Sfrp2) reduces fibrosis and improves cardiac function in a rat model of myocardial infarction."
01/01/2014 - "Here, we studied the role of two extracellular Wnt antagonists, secreted frizzled-related protein-1 (SFRP1) and frizzled-related protein (FRZB) on lung fibrosis in vitro and in vivo. "
05/01/2008 - "Previous in vitro studies identified secreted frizzled related protein 1 (SFRP1) as a candidate pro-proliferative signal during prostatic development and cancer progression. "
11/01/2015 - "Deregulation of secreted frizzled-related protein 2 (sFRP2) has been found in many types of cancer. "
07/01/2015 - "Deregulation of secreted frizzled-related protein 1 (SFRP1) has been found in many types of cancer. "
01/01/2015 - "Secreted frizzled-related protein 4 and its implications in cancer and apoptosis."
01/01/2014 - "Secreted frizzled related protein 1 (SFRP1) functions as an important inhibitor of the Wnt pathway and is a known tumor suppressor gene, which is epigenetically silenced in a variety of tumors e.g. "
|5.||Colorectal Neoplasms (Colorectal Cancer)
01/01/2011 - "The aim of this study was to investigate the diagnostic and prognostic significance of the methylation status of secreted frizzled-related protein 2 (SFRP2) in colorectal cancer (CRC). "
03/15/2012 - "The combination of oligoamines and DFMO results in a synergistic re-expression of aberrantly silenced tumour-suppressor genes, including SFRP2 (secreted frizzled-related protein 2), which encodes a Wnt signalling pathway antagonist and plays an anti-tumorigenic role in colorectal cancer. "
05/01/2011 - "The Dickkopf-1 (DKK1) and Secreted Frizzled Related Protein 1 (SFRP1) genes encode extracellular inhibitors of Wnt signaling that are frequently silenced by promoter hypermethylation in colorectal cancer (CRC). "
01/01/2011 - "Diagnostic and prognostic value of the methylation status of secreted frizzled-related protein 2 in colorectal cancer."
11/01/2007 - "[Hypermethylation and regulation of expression of secreted frizzled-related protein genes in colorectal tumor]."
|1.||Proteins (Proteins, Gene)
|2.||Janus Kinase 3
|3.||Sphingomyelin Phosphodiesterase (Sphingomyelinase)
|4.||Progesterone Receptors (Progesterone Receptor)
|5.||retinoic acid receptor beta
|6.||Estrogen Receptor alpha
|8.||fibroblast growth factor 23
|9.||Fibroblast Growth Factor 7
|10.||Glycogen Synthase Kinases
|1.||Drug Therapy (Chemotherapy)