phospholipase D1

Subscribe to Selected New Research on phospholipase D1

17 relevant articles (0 outcomes, 2 trials/studies) found for this Bio-Agent

Description: activated by Arf family GTPases & dependent upon phosphatidylinositol-4,5-bisphosphate (PIP2); has 2 splice forms, PLD1a & PLD1b; has been sequenced; RefSeq NM_002662 (human), NM_008875 (mouse), NM_030992 (rat)

Also Known As:

PLD-1a; PLD-1b; PLD1 (enzyme); PLD1 protein, human; Phosphatidylcholine-hydrolyzing phospholipase D1; Pld1 protein, mouse; Pld1 protein, rat; Pld1a protein, mouse; Pld1a protein, rat; Pld1b protein, mouse; Pld1b protein, rat; Plda protein, rat; Pldb protein, rat; hPLD1 protein; mPLD1 protein; phosphatidylcholine-specific phospholipase D1; phosphatidylcholine-specific phospholipase D1a; phosphatidylcholine-specific phospholipase D1b; phospholipase D1, mouse; phospholipase D1, phophatidylcholine-specific protein, human; phospholipase D1, rat; rPLD1 protein

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1

Enzymes: 25587

Hydrolases: 580

Esterases: 227

Phosphoric Diester Hydrolases: 133

Phospholipases: 1120

Phospholipase D: 276

phospholipase D1: 17

Experts

1.	Min, Do Sik: 4 articles (02/2008 - 02/2005)
2.	Kim, Yong-Sun: 3 articles (07/2007 - 02/2005)
3.	Choi, Eun-Kyoung: 3 articles (07/2007 - 02/2005)
4.	Jin, Jae-Kwang: 3 articles (07/2007 - 02/2005)
5.	Park, Mi Hee: 2 articles (02/2008 - 10/2006)
6.	Kim, Jae-Il: 2 articles (07/2007 - 02/2005)
7.	Kozlowski, Piotr B: 2 articles (07/2007 - 10/2006)
8.	Kim, Nam-Ho: 2 articles (10/2006 - 02/2005)
9.	Nozawa, Yoshinori: 2 articles (12/2005 - 01/2004)
10.	Ohguchi, Kenji: 2 articles (12/2005 - 01/2004)

Related Diseases

1.	Melanoma (Melanoma, Malignant) 07/01/2003 - "Immunoprecipitation study showed that phospholipase D1 and protein kinase C alpha are associated physiologically in resting melanoma cells. " 07/01/2003 - "These results suggest that upregulation of phospholipase D1 and protein kinase C alpha plays a part in the progression of acral lentiginous melanoma from the radial growth phase to the vertical growth phase. " 07/01/2003 - "Both phospholipase D1 and protein kinase C alpha were strongly expressed in primary and metastatic lesions of superficial spreading melanoma. " 07/01/2003 - "In addition, the mechanism of regulation of phospholipase D1 by protein kinase C alpha was examined in a human melanoma cell line HM3KO using an adenovirus-mediated gene transfer technique. " 06/28/2002 - "The regulation of phospholipase D1 (PLD1), which has been shown to be activated by protein kinase C (PKC) alpha, was investigated in the human melanoma cell lines. " Order ALL the reference details at left...
2.	Neoplasms (Cancer) 02/01/2005 - "Our studies identify phospholipase D1 as a critical downstream mediator of H-Ras-induced tumor formation." 07/01/2003 - "Conversely, in acral lentiginous melanoma lesions, the expression of these two proteins increased dramatically with tumor progression; the expression of both phospholipase D1 and protein kinase C alpha was almost negative in the radial growth phase of primary acral lentiginous melanoma lesions, and increased synchronously in a progression-related manner in advanced acral lentiginous melanoma lesions, including vertical growth phase and metastatic lesions. " Order ALL the reference details at left...
3.	Alzheimer Disease (Alzheimer's Disease) 10/30/2006 - "Phospholipase D1 is up-regulated in the mitochondrial fraction from the brains of Alzheimer's disease patients." 07/01/2007 - "Phospholipase D1 is associated with amyloid precursor protein in Alzheimer's disease." 02/07/2006 - "Phospholipase D1 corrects impaired betaAPP trafficking and neurite outgrowth in familial Alzheimer's disease-linked presenilin-1 mutant neurons." Order ALL the reference details at left...
4.	Experimental Melanoma 01/30/2004 - "Involvement of phospholipase D1 in melanogenesis of mouse B16 melanoma cells." 12/01/2005 - "Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells." Order ALL the reference details at left...
5.	Coffin-Lowry Syndrome (Syndrome, Coffin-Lowry) 01/01/2009 - "The Coffin-Lowry syndrome-associated protein RSK2 controls neuroendocrine secretion through the regulation of phospholipase D1 at the exocytotic sites." Order ALL the reference details at left...

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