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6- ((2- (dimethylamino)ethyl)amino)- 3- hydroxy- 7H- indeno(2,1- c)quinolin- 7- one

inhibits topoisomerase I and topoisomerase II; structure in first source
Also Known As:
TAS 103; TAS-103; TAS-103 free base; 7H-Indeno(2,1-c)quinolin-7-one, 6-((2-(dimethylamino)ethyl)amino)-3-hydroxy-
Networked: 18 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. Kobunai, T: 2 articles (11/2001 - 05/2000)
2. Yamada, Y: 2 articles (11/2001 - 05/2000)
3. Fujimoto, Shuichi: 1 article (10/2007)
4. Chijiiwa, Kazuo: 1 article (01/2005)
5. Igarashi, Tomonori: 1 article (01/2005)
6. Itoh, Hideaki: 1 article (01/2005)
7. Izumi, Hiroto: 1 article (01/2005)
8. Kohno, Kimitoshi: 1 article (01/2005)
9. Matsuo, Ken-ichi: 1 article (01/2005)
10. Niina, Ichiro: 1 article (01/2005)

Related Diseases

1. Neoplasms (Cancer)
2. Small Cell Lung Carcinoma (Small Cell Lung Cancer)
3. Lewis Lung Carcinoma
4. Pancreatic Neoplasms (Pancreatic Cancer)
5. Colorectal Neoplasms (Colorectal Cancer)

Related Drugs and Biologics

1. Antineoplastic Agents (Antineoplastics)
2. trioctyl phosphine oxide (TOPO)
3. Type I DNA Topoisomerases (Topoisomerase I)
4. Member 1 Subfamily B ATP Binding Cassette Transporter
5. DNA (Deoxyribonucleic Acid)
6. Cisplatin (Platino)
7. quinoline
8. Topoisomerase Inhibitors
9. Investigational Drugs
10. XR5944

Related Therapies and Procedures

1. Drug Therapy (Chemotherapy)
2. Therapeutics