spectrin St. Claude

277-kDa alpha-spectrin that results from replacement of thymine with guanine in the 3' acceptor splice site of exon 20; two forms, 108-kDa and 277-kDa, could result from introduced termination codon

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Spectrin: 919
      - spectrin St. Claude: 3
  - Cytoskeletal Proteins: 739
    - Spectrin: 919
      - spectrin St. Claude: 3

Experts

1.	Gallagher, Patrick G: 1 article (01/2004)
2.	Mootien, S: 1 article (01/2004)

Related Diseases

1.	Hereditary Elliptocytosis 10/01/1998 - "Reduced spectrin-ankyrin binding in a South African hereditary elliptocytosis kindred homozygous for spectrin St Claude."
2.	Anemia 06/15/1997 - "Spectrin St Claude, a splicing mutation of the human alpha-spectrin gene associated with severe poikilocytic anemia."
3.	Hereditary Pyropoikilocytosis 01/01/2004 - "Hereditary pyropoikilocytosis and the spectrin St. Claude allele."

Related Drugs and Biologics

1.	Spectrin
2.	Ankyrins