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ZM 252868
Also Known As:
ZM-252868; ZM25268
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinazolines: 402
ZM 252868: 1
Related Diseases
1.
Ovarian Neoplasms (Ovarian Cancer)
03/01/1999 - "
Inhibition of transforming growth factor alpha (TGF-alpha)-mediated growth effects in ovarian cancer cell lines by a tyrosine kinase inhibitor ZM 252868.
"
2.
Carcinoma (Carcinomatosis)
03/01/1999 - "
These data indicate that the EGF receptor-targeted TK inhibitor ZM 252868 can inhibit growth of ovarian carcinoma cells in vitro consistent with inhibition of tyrosine phosphorylation at the EGF receptor.
"
03/01/1999 - "
The modulating effects of the epidermal growth factor (EGF) receptor-specific tyrosine kinase inhibitor ZM 252868 on cell growth and signalling have been evaluated in four ovarian carcinoma cell lines PE01, PE04, SKOV-3 and PE01CDDP.
"
Related Drugs and Biologics
1.
ErbB Receptors (EGF Receptor)
2.
Transforming Growth Factor alpha (TGF-alpha)
3.
Tyrosine (L-Tyrosine)
4.
Epidermal Growth Factor (EGF)
5.
Tyrosine Kinase Inhibitors