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SPA-S-753

Also Known As:

N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate

Networked: 2 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Polyenes: 164
        SPA-S-753: 2

Experts

1.	Clemons, K V: 1 article (02/2001)
2.	Stevens, D A: 1 article (02/2001)

Related Diseases

1.	Infections 02/01/2001 - "Overall, cure rates were similar, amphotericin B at 1 mg/kg cured three and SPA-S-753 at 10 mg/kg cured four mice of infection in both organs. "
2.	Meningoencephalitis 03/01/1997 - "A new member of the polyene family, N-dimethylaminoacetyl-partricin A 2-dimethylaminoethylamide diaspartate (SPA), was investigated and was found to be more effective than amphotericin B (i) in vivo by enhancing mouse resistance to cryptococcal meningoencephalitis and (ii) in vitro by potentiating the anticryptococcal activity of murine microglial cells."

Related Drugs and Biologics

1.	Amphotericin B (Amphotericin)
2.	Dihydrotachysterol (AT 10)