3,7- dihydro- 3- methyl- 7- ((5- methyl- 1,2,4- oxadiazol- 3- yl)methyl)- 1H-purine-2,6-dione

Also Known As:

1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7-((5-methyl-1,2,4-oxadiazol-3-yl)methyl)-; 3,7-dihydro-3-methyl-7-((5-methyl-1,2,4-oxadiazol-3-yl)methyl)-1H-purine-2,6-dione; CH 13584; CH-13584; KHL-8425

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Oxazoles: 89
      - Oxadiazoles: 146
        3,7-dihydro-3-methyl-7-((5-methyl-1,2,4-oxadiazol-3-yl)methyl)- 1H-purine-2,6-dione: 2
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - 3,7-dihydro-3-methyl-7-((5-methyl-1,2,4-oxadiazol-3-yl)methyl)- 1H-purine-2,6-dione: 2

Related Diseases

1.	Cough 04/01/1997 - "CH-13584 was also effective on capsaicine spray and mechanical irritation-induced cough in guinea-pig and rabbit, respectively. " 04/01/1997 - "CH-13584 showed acute and chronic antitussive activity on citric acid spray-evoked cough model in guinea-pig. " 12/01/1998 - "CH-13584 (formerly: KHL-8425, 1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7[(5-methyl-1,2,4-oxadiazol-3-yl)methyl], CAS 115779-20-9) showed antitussive effect on the citric acid spray-induced cough model. "
2.	Chronic Cough 04/01/1997 - "CH-13584 (formerly: KHL-8425, 1H-purine-2,6-dione, 3,7-dihydro-3-methyl-7[(5-methyl-1,2,4-oxadiazol-3-yl)methyl], CAS 115779-20-9) is a new xanthine derivative synthesized with the purpose to develop a highly safe compound against several pulmonary disorders, especially for the treatment of acute and chronic cough. "

Related Drugs and Biologics

1.	Citric Acid (Citrate)
2.	Antitussive Agents (Antitussives)
3.	purine
4.	Xanthine
5.	Capsaicin (Zostrix)