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SWR 215

structure given in first source

Also Known As:

(((1,2-dihydro-2-oxo-4-quinolinyl)methyl)thio)-N-(((4-(1-piperidinylmethyl)-2-pyridinyl)oxy)-2-butenyl)acetamide; SWR-215

Networked: 1 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Piperidines: 17
    - SWR 215: 1
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinolines: 146
      - SWR 215: 1

Related Diseases

1.	Peptic Ulcer (Peptic Ulcers) 01/01/1997 - "These results suggest that SWR-215 possesses both durable antisecretory and mucosal protective effects, and is expected to be a useful drug for the treatment of patients with peptic ulcers."
2.	Fistula 01/01/1997 - "In gastric secretion studies, SWR-215 exhibited potent and durable inhibitory effects, and the antisecretory activities were much stronger than that of roxatidine acetate hydrochloride (roxatidine): 5 times stronger on basal acid secretion in pylorus ligated rats, 11 times stronger on histamine-stimulated acid secretion in acute fistula rats, and 2 times stronger on histamine stimulated acid secretion in Heidenhain-pouch dogs, respectively. "

Related Drugs and Biologics

1.	Histamine (Histamine Dihydrochloride)
2.	Acids
3.	roxatidine acetate (roxatidine)