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N- ((3- p- fluorophenyl- 1- propyl)- 4- methyl- 4- piperidinyl)- 4- amino- 5- iodo- 2- methoxybenzamide

SPECT radiotracer for serotonin 2A receptors; structure in first source

Also Known As:

R 93274; R 93274, 125I-labeled; R-93274; R93274

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Leysen, J E: 1 article (07/2002)
2.	Luyten, W H M L: 1 article (07/2002)
3.	Meert, T: 1 article (07/2002)
4.	Megens, A: 1 article (07/2002)
5.	Van Oekelen, D: 1 article (07/2002)

Related Diseases

1.	Tremor (Tremors) 07/01/2002 - "In contrast to SB-242084, the selective 5-HT(2A)R antagonist R93274 as well as the non-selective 5-HT(2A)R antagonists (R99647, ketanserin, risperidone, pipamperone and mianserin) significantly inhibited tryptamine-induced forepaw treading and tremors, and reversed peripherally mediated cyanosis into hyperaemia; only the 5-HT(2A/C)R antagonists R99647 and mianserin inhibited the tryptamine-induced hunched back. "
2.	Cyanosis 07/01/2002 - "In contrast to SB-242084, the selective 5-HT(2A)R antagonist R93274 as well as the non-selective 5-HT(2A)R antagonists (R99647, ketanserin, risperidone, pipamperone and mianserin) significantly inhibited tryptamine-induced forepaw treading and tremors, and reversed peripherally mediated cyanosis into hyperaemia; only the 5-HT(2A/C)R antagonists R99647 and mianserin inhibited the tryptamine-induced hunched back. "

Related Drugs and Biologics

1.	Risperidone (Risperdal Consta)
2.	Mianserin
3.	Ketanserin
4.	6- chloro- 5- methyl- 1- ((2- (2- methylpyrid- 3- yloxy)pyrid- 5- yl)carbamoyl)indoline
5.	tryptamine
6.	pipamperone