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L 738167
structure in first source
Also Known As:
2-((p-toluenesulfonyl)amino)-3-(((5,6,7,8-tetrahydro-4-oxo-5-(2-(piperidin-4-yl)ethyl)-4H-pyrazolo(1,5-a)(1,4)diazepin-2-yl)carbonyl)amino)propionic acid; L 738,167; L-738,167; L-738167
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azepines: 11
L 738167: 2
Organic Chemicals: 133
Amides: 2428
Sulfonamides: 2809
L 738167: 2
Sulfur Compounds: 278
Sulfones: 534
Sulfonamides: 2809
L 738167: 2
Related Diseases
1.
Thrombosis (Thrombus)
05/01/1997 - "
In an anesthetized canine model of coronary artery electrolytic lesion, L-738,167 elicited dose-dependent (3, 4, 4.5 and 5 micrograms/kg i.v.) decreases in incidence of occlusion, reductions in thrombus mass and elevations in bleeding time.
"
08/05/1997 - "
Significant reductions in thrombus mass and complete prevention of myocardial ischemia and infarction were achieved with a single 100- to 300-microg/kg dose of L-738,167 pretreatment and with two 100-microg/kg doses administered 12 hours before and after initiation of vessel injury.
"
2.
Myocardial Ischemia (Ischemic Heart Diseases)
08/05/1997 - "
Significant reductions in thrombus mass and complete prevention of myocardial ischemia and infarction were achieved with a single 100- to 300-microg/kg dose of L-738,167 pretreatment and with two 100-microg/kg doses administered 12 hours before and after initiation of vessel injury.
"
3.
Infarction (Infarctions)
08/05/1997 - "
Significant reductions in thrombus mass and complete prevention of myocardial ischemia and infarction were achieved with a single 100- to 300-microg/kg dose of L-738,167 pretreatment and with two 100-microg/kg doses administered 12 hours before and after initiation of vessel injury.
"