|1.||Boldogh, Istvan: 5 articles (04/2008 - 04/2003)|
|2.||Kruzel, Marian L: 5 articles (04/2008 - 04/2003)|
|3.||Janusz, Maria: 4 articles (08/2010 - 10/2002)|
|4.||Lisowski, Józef: 4 articles (01/2009 - 10/2002)|
|5.||Janusz, M: 3 articles (01/2013 - 01/2001)|
|6.||Macała, Józefa: 3 articles (08/2010 - 02/2005)|
|7.||Stewart, Michael G: 3 articles (01/2010 - 07/2006)|
|8.||Bacsi, Attila: 3 articles (01/2008 - 01/2006)|
|9.||Zabłocka, Agnieszka: 2 articles (08/2010 - 02/2005)|
|10.||Banks, Duncan: 2 articles (01/2010 - 07/2006)|
|1.||Alzheimer Disease (Alzheimer's Disease)
01/01/2013 - "Beneficial effects of PRP/Colostrinin in the case of Alzheimer's disease were shown in double-blind placebo-controlled trials, in long-term open-label studies and in multicenter clinical trials. "
02/01/2004 - "This study was designed to confirm or negate findings from earlier trials demonstrating that Colostrinin, a novel compound derived from ewes' colostrum, has potential in the treatment of mild or moderate Alzheimer's Disease (AD). "
01/01/1999 - "These observations prompted us to study the effect of Colostrinin on patients with Alzheimer's disease (AD). "
03/01/2009 - "New insights into clinical trial for Colostrinin in Alzheimer's disease."
12/01/2001 - "Also, it is hoped that the beneficial use of colostrinin in Alzheimer's Disease (AD), recently reported elsewhere, will revive interest in its clinical application for treatment and/or prophylaxis of many age-related disorders."
01/01/2006 - "Colostrinin (CLN), a uniform mixture of low-molecular weight, proline-rich polypeptides, induces neurite outgrowth of pheochromocytoma cells, extends the lifespan of diploid fibroblast cells, inhibits beta amyloid-induced apoptosis and resulted in improved cognitive function when administered to Alzheimer's patients. "
04/01/2003 - "In previous studies we showed that colostrinin (CLN), a complex of proline-rich polypeptides derived from ovine colostrum, induces mitogenic stimulation, as well as a variety of cytokines in human peripheral blood leukocytes, and possesses antioxidant activity in pheochromocytoma (PC12) cells. "
04/01/2007 - "Colostrinin (CLN), a uniform mixture of low-molecular weight, proline-rich polypeptides, induces neurite outgrowth of pheochromocytoma cells and inhibits beta amyloid-induced apoptosis. "
|3.||Neurodegenerative Diseases (Neurodegenerative Disease)
10/01/2008 - "Although clinical management of neurodegenerative diseases usually involves symptomatic treatment, Colostrinin() (CLN), which has efficacy in counteracting neural degradation and in stimulating neural growth, might prove to be a more effective means to deal with the causes of Alzheimer's and other neurodegenerative diseases. "
10/01/2008 - "Colostrinin: a naturally occurring compound derived from mammalian colostrum with efficacy in treatment of neurodegenerative diseases, including Alzheimer's."
01/01/2013 - "Biological response modifying activity of PRP/Colostrinin can play an important role in its use in the treatment of Alzheimer's disease and suggests its application beyond neurodegenerative disorders."
03/15/2007 - "It was previously reported that colostrinin (CLN), a proline-rich peptide derived from colostrum, reduces fibril content and protects neuroblastoma cells against Abeta peptide-induced toxicity. "
08/01/2005 - "Protective effect of colostrinin on neuroblastoma cell survival is due to reduced aggregation of beta-amyloid."
01/01/1999 - "The results obtained showed that oral administration of Colostrinin improves the outcome of AD patients with mild to moderate dementia. "
07/01/2006 - "Colostrinin (CLN) is a biologically active proline-rich polypeptide which has therapeutic potential for the alleviation of memory deficits in age-related dementias in a number of human conditions, particularly Alzheimer's disease. "
|3.||Amyloid (Amyloid Fibrils)
|1.||Activities of Daily Living (ADL)