marrubiin

01/01/2023 - "Since apoptosis plays a significant role in the plaque rupture, the study also evaluated the protective effects of marrubiin on the expression of key genes involved in apoptotic pathways. "

09/01/2017 - "Treatment with marrubiin effectively improved lesion regression and inhibited toxicity in the mouse model of endometriosis. "
09/01/2017 - "Marrubiin significantly inhibited endometrial lesions and monocyte chemotaxis in the mice with endometriosis, and reduced U937 cell migration. "
09/01/2017 - "The mice with endometriosis were then treated with 12, 25 or 50 mg/kg marrubiin. "
09/01/2017 - "The aim of the present study was to evaluate the protective effects of marrubiin on endometriosis through suppression of the expression of regulated on activation, normal T cell expressed and secreted (RANTES). "
09/01/2017 - "Protective effects of marrubiin improve endometriosis through suppression of the expression of RANTES."

01/01/2023 - "Based on our findings, marrubiin is recommended as a preventive/therapeutic treatment for diseases caused by elevated intracellular reactive oxygen species levels in cardiovascular diseases."
03/25/2019 - "Horehound (Marrubium vulgare) is a medicinal plant whose signature bioactive compounds, marrubiin and related furanoid diterpenoid lactones, have potential applications for the treatment of cardiovascular diseases and type II diabetes. "

09/01/2017 - "These findings indicated that the protective effect of marrubiin improved endometriosis in the mice through the suppression of inflammation and downregulation of the expression of RANTES, followed by mediation of the levels of calcium, PGE2 and TXB2."

04/01/2020 - "In our study, we conclude that M.vulgare and marrubiin can be used as natural antioxidants and antifungal agent for treatment of skin dermatophyte infections."