pseudophrynaminol

blocks nicotinic receptor channels; RN given for (3aR-(3aalpha(E),8aalpha))-isomer; structure in first source

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Pheochromocytoma 03/07/1997 - "(+/-)-Pseudophrynaminol inhibited carbamylcholine-elicited sodium-22 influx with an IC50 value of about 0.3 microM in both rat pheochromocytoma PC12 cells (ganglionic-type nicotinic receptor) and human medulloblastoma TE671 cells (neuromuscular-type nicotinic receptor). "
2.	Medulloblastoma 03/07/1997 - "(+/-)-Pseudophrynaminol inhibited carbamylcholine-elicited sodium-22 influx with an IC50 value of about 0.3 microM in both rat pheochromocytoma PC12 cells (ganglionic-type nicotinic receptor) and human medulloblastoma TE671 cells (neuromuscular-type nicotinic receptor). "

1.	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)
2.	Carbachol (Carbastat)
3.	Sodium-22