|1.||Ishii, Genichiro: 6 articles (01/2016 - 01/2013)|
|2.||Yu, Cheng-Chia: 6 articles (09/2015 - 01/2011)|
|3.||Torigoe, Toshihiko: 6 articles (12/2014 - 07/2012)|
|4.||Sato, Noriyuki: 6 articles (12/2014 - 07/2012)|
|5.||Lo, Wen-Liang: 6 articles (06/2013 - 07/2009)|
|6.||Wicha, Max S: 6 articles (01/2013 - 11/2007)|
|7.||Umemura, Shigeki: 5 articles (01/2016 - 01/2013)|
|8.||Goto, Koichi: 5 articles (01/2016 - 01/2013)|
|9.||Matsumoto, Shingo: 5 articles (01/2016 - 01/2013)|
|10.||Niho, Seiji: 5 articles (01/2016 - 01/2013)|
06/01/2015 - "ALDH1 expression in tumor tissues was significantly greater than that in adjacent normal tissues. "
01/01/2015 - "Although CSCs have been identified in some different types of pediatric solid tumors, there have been no studies regarding the efficacy of ALDH1 as a marker for CSCs. "
01/01/2013 - "In subgroup analysis, those subgroups with no positive, one positive or two positive results in immunohistochemistry for ALDH1 and SOX2 expression had estimated 5-year cancer-specific survival rates of 80%, 49% and 22%, respectively (P<0.001). "
01/01/2016 - "This study attempted to investigate the value of ALDH1 as a predictive marker of chemosensitivity and its prognostic value in cervical cancer patients treated with NAC. "
08/01/2014 - "The objectives of this study were (i) to evaluate the patterns of CD44 and ALDH1 expression in the tumor center and in the invasive front, as well as in adjacent non-tumor epithelium, and (ii) to correlate these findings with clinical parameters. "
|2.||Neoplasm Metastasis (Metastasis)
08/01/2015 - "However, in the identified studies, ALDH1 expression was highly correlated with lymph node metastasis (OR=1.97, 95% CI: 1.16-3.34, P=0.01), tumour TNM staging (OR=1.68, 95% CI 1.28-2.22, P=0.0002), decreased overall survival (relative risk [RR]: 1.97,95% CI: 1.16-3.34, P =0.01) and decreased disease free survival (RR: 1.63, 95% CI: 1.01-2.64, P=0.05). "
05/01/2013 - "In the present study, HPV genotypes and expression of ALDH1 and p16 was analyzed in 40 paired OSCC and metastases. "
03/01/2015 - "Multivariate Cox proportional hazard model revealed that ALDH1 (hazard ratio [HR] = 5.682, P = 0.038) was significantly associated with metastasis. "
01/01/2015 - "The analysis of these data showed that ALDH1 expression was highly correlated with lymph node metastasis (pooled OR = 1.45, 95% CI: 1.04-2.02, P = 0.027), decreased overall survival (pooled RR: 2.25, 95% CI: 1.15-4.41, P = 0.019), and decreased disease-free survival (pooled RR: 1.63, 95% CI: 1.01-2.64, P = 0.047). "
11/01/2014 - "On univariate analysis, ALDH1 expression and grade were associated with survival but ages, number of lymph node metastasis, race, or grade were not associated. "
|3.||Breast Neoplasms (Breast Cancer)
06/01/2012 - "ALDH1 expression is frequent in tumour-associated stromal cells of triple negative breast cancer and is associated with better outcome. "
01/01/2014 - "Several studies have reported that ALDH1 expression is associated with poor prognosis in breast cancer. "
10/01/2013 - "In this study, we performed flow cytometry and immunohistochemistry to measure the expression of ALDH1 in 10 breast cancer cell lines and in a set of tissue microarrays consisting of 101 breast cancer tissues from the Chinese population. "
07/09/2013 - "In this study, we used ALDH1 as a CSC marker and determined whether ALDH1 expression correlated with clinical outcome in young women with breast cancer. "
06/01/2012 - "In the present study, third-sphere forming (3-S) CSC-like cells, which showed elevated CSC surface markers (ALDH1(+) and CD44(+)/CD24(-/low)) and sphereforming capacity as well as migration and invasion capacities, were cultured and isolated from breast cancer MCF-7 parental cells, to evaluate the role of miR-21 in regulating the CSC-like cell biological features, especially EMT. "
|4.||Rectal Neoplasms (Rectal Cancer)
02/01/2015 - "The aim of this study was to investigate the expression of CD133 and ALDH1 and to analyze the predictive and prognostic roles in patients with rectal cancer after chemoradiotherapy. "
02/01/2015 - "Expression of ALDH1 indicates a more aggressive feature of stage III rectal cancer and can stratify stage III rectal cancer into different survival groups."
02/01/2015 - "Cox multivariate analysis demonstrated that high ALDH1 expression (HR, 5.425; 95% CI, 1.116-26.373; P=0.036), cT (HR, 12.861; 95% CI, 2.188-75.591; P=0.005), and pN2 (HR, 28.481; 95% CI, 4.757-170.518; P<0.001) were independently associated with overall survival in 51 patients with stage III rectal cancer. "
02/01/2015 - "The 5-year overall survival rates were lower in patients with high ALDH1 expression compared to low ALDH1 expression in stage III rectal cancer (61.0% vs. 89.7%, P=0.031). "
02/01/2015 - "We analyzed the expression levels of ALDH1 and CD133 in patients with middle and lower rectal cancers who underwent preoperative chemoradiotherapy between March 2005 and December 2011. "
|4.||aldehyde dehydrogenase 1
|5.||Proteins (Proteins, Gene)
|6.||tumor-associated antigen GA733
|9.||Carrier Proteins (Binding Protein)
|10.||nestin (nestin protein)
|1.||Heterologous Transplantation (Xenotransplantation)
|3.||Drug Therapy (Chemotherapy)