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N- benzyloxycarbonyl- thioprolyl- thioprolinal- dimethylacetal
structure given in first source
Also Known As:
ZTTA
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Sulfur Compounds: 278
Thiazoles: 392
N-benzyloxycarbonyl-thioprolyl-thioprolinal-dimethylacetal: 2
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Thiazoles: 392
N-benzyloxycarbonyl-thioprolyl-thioprolinal-dimethylacetal: 2
Related Diseases
1.
Ischemia
11/01/1996 - "
ZTTA at 6 mg/kg, administered immediately after blood flow reperfusion, significantly reduced the increase in working memory errors expected to occur 24 h after 5 min of ischemia.
"
05/14/1999 - "
We investigated the effects of the prolyl endopeptidase inhibitors 1-[1-(Benzyloxycarbonyl)-L-prolyl]prolinal (Z-Pro-Prolinal) and N-benzyloxycarbonyl-thioprolyl-thioprolinal-dimethylaceta l (ZTTA) on delayed neuronal death induced by four-vessel-occlusion transient ischemia in rats.
"
2.
Brain Ischemia (Cerebral Ischemia)
11/01/1996 - "
ZTTA, a postproline cleaving enzyme inhibitor, improves cerebral ischemia-induced deficits in a three-panel runway task in rats.
"
11/01/1996 - "
We investigated the effect of N-benzyloxycarbonyl-thioprolyl-thioprolinal-dimethylaceta l (ZTTA), a novel postproline cleaving enzyme (prolyl endopeptidase, PPCE) inhibitor, on the in vitro activity of rat brain PPCE and memory impairment induced by cerebral ischemia.
"
Related Drugs and Biologics
1.
Prolyl Oligopeptidases
2.
Enzymes
3.
Enzyme Inhibitors (Inhibitors, Enzyme)
4.
prolinal
5.
N-benzyloxycarbonylprolylprolinal